PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke

Project Information

PRECIOUS

Grant agreement ID: 634809

DOI 10.3030/634809

Project closed

EC signature date 7 April 2015

Start date 1 June 2015

End date 30 November 2022

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 5 334 687,71

EU contribution € 5 334 687,21

Coordinated by

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

Deliverables

Websites, patent fillings, videos etc. (1)

Launch of website and social media accounts

Documents, reports (5)

Report on potential (of trial results) for new Treatment Guidelines in partner countries

Report on potential of trial results for new Treatment Guidelines in partner countries

Statistical Analysis Plan
Final dissemination report
Initial dissemination report
Dissemination plan

Publications

Peer reviewed articles (10)

PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke—statistical analysis plan of a randomised, open, phase III, clinical trial with blinded outcome assessment

Author(s): Jeroen C. de Jonge, Lisa J. Woodhouse, Hendrik Reinink, H. Bart van der Worp, Philip M. Bath
Published in: Trials, Issue 21/1, 2020, ISSN 1745-6215
Publisher: BioMed Central
DOI: 10.1186/s13063-020-04717-0

Surgical Decompression for Space-Occupying Hemispheric Infarction: A Systematic Review and Individual Patient Meta-analysis of Randomized Clinical Trials

Author(s): Reinink H, Jüttler E, Hacke W, et al.
Published in: JAMA Neurol., Issue 2021;78(2), 2021, Page(s) 208–216, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2020.3745

Preventive ceftriaxone in patients at high risk of stroke-associated pneumonia. A post-hoc analysis of the PASS trial

Author(s): Wouter M. Sluis; Willeke F. Westendorp; Diederik van de Beek; Paul J. Nederkoorn; H. Bart van der Worp
Published in: PLoS One, Issue 30;17(12):e0279700, 2022, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0279700

Treatment Restrictions and the Risk of Death in Patients With Ischemic Stroke or Intracerebral Hemorrhage

Author(s): Hendrik Reinink, Burak Konya, Marjolein Geurts, L. Jaap Kappelle, H. Bart van der Worp
Published in: Stroke, Issue 51/9, 2020, Page(s) 2683-2689, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.120.029788

Signs of Pulmonary Infection on Admission Chest Computed Tomography Are Associated With Pneumonia or Death in Patients With Acute Stroke

Author(s): Jeroen C. de Jonge, Richard A.P. Takx, Frans Kauw, Pim A. de Jong, Jan W. Dankbaar, H. Bart van der Worp
Published in: Stroke, Issue 51/6, 2020, Page(s) 1690-1695, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.120.028972

Regulatory delays in a multinational clinical stroke trial

Author(s): Jeroen C de Jonge, Hendrik Reinink, Bridget Colam, Iris Alpers, Alfonso Ciccone, Laszlo Csiba, Janika Kõrv, Iwona Kurkowska-Jastrzebska, Malcolm R Macleod, George Ntaios, Götz Thomalla, Philip M Bath, H Bart van der Worp
Published in: European Stroke Journal, Issue 6/2, 2021, Page(s) 120-127, ISSN 2396-9873
Publisher: SAGE Publications
DOI: 10.1177/23969873211004845

PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment

Author(s): Hendrik Reinink, Jeroen C de Jonge, Philip M Bath, Diederik van de Beek, Eivind Berge, Saskia Borregaard, Alfonso Ciccone, Laszlo Csiba, Jacques Demotes, Diederik W Dippel, Janika Kõrv, Iwona Kurkowska-Jastrzebska, Kennedy R Lees, Malcolm R Macleod, George Ntaios, Gary Randall, Götz Thomalla, H Bart van der Worp
Published in: European Stroke Journal, Issue 3/3, 2018, Page(s) 291-298, ISSN 2396-9873
Publisher: SAGE Publishing
DOI: 10.1177/2396987318772687

Fever worsens outcomes in animal models of ischaemic stroke: A systematic review and meta-analysis

Author(s): Jeroen C de Jonge, Justin Wallet, H. Bart van der Worp
Published in: European Stroke Journal, Issue 4/1, 2018, Page(s) 29-38, ISSN 2396-9873
Publisher: SAGE Publishing
DOI: 10.1177/2396987318776421

Quality of dying after acute stroke

Author(s): Hendrik Reinink; Marjolein Geurts; Marjolein Geurts; Constance Melis-Riemens; Annemarie Hollander; Jaap Kappelle; Bart van der Worp
Published in: European Stroke Journal, Issue 2021;6(3), 2021, Page(s) 268-275, ISSN 2396-9873
Publisher: SAGE Publications Ltd
DOI: 10.1177/23969873211041843

Timing and causes of death after endovascular thrombectomy in patients with acute ischemic stroke

Author(s): Sluis WM, Hinsenveld WH, Goldhoorn R-JB, et al.
Published in: European Stroke Journal, Issue 2022;0(0), 2022, ISSN 2396-9873
Publisher: SAGE Publications Ltd
DOI: 10.1177/23969873221143210

Other (1)

Prevention of complications to Improve outcome in elderly patients with acute stroke - A randomised clinical trial

Author(s): Bart van der Worp, Bart van der Worp
Published in: ISRCTN registry, Issue ISRCTN82217627, 2015
Publisher: Springer Nature
DOI: 10.1186/isrctn82217627