Cholesterol and Sugar Uptake Mechanisms

Project Information

CSUMECH

Grant agreement ID: 637372

DOI

10.3030/637372

Project closed

EC signature date 14 April 2015

Start date 1 July 2015

End date 31 December 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 848,00

EU contribution

€ 1 499 848,00

Coordinated by

AARHUS UNIVERSITET
Denmark

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Mechanistic Insight into Lipid Binding to Yeast Niemann Pick Type C2 Protein

Author(s): Laust Moesgaard, Daniel Petersen, Maria Szomek, Peter Reinholdt, Mikael B. L. Winkler, Kelly May Frain, Peter Müller, Bjørn Panyella Pedersen, Jacob Kongsted, Daniel Wüstner
Published in: Biochemistry, Issue 59/45, 2020, Page(s) 4407-4420, ISSN 0006-2960
Publisher: American Chemical Society
DOI: 10.1021/acs.biochem.0c00574

Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family

Author(s): Tânia Filipa Custódio, Peter Aasted Paulsen, Kelly May Frain, Bjørn Panyella Pedersen
Published in: Life Science Alliance, Issue 4/4, 2021, Page(s) e202000858, ISSN 2575-1077
Publisher: Life Science Alliance, LLC
DOI: 10.26508/lsa.202000858

Serine phosphorylation regulates the P-type potassium pump KdpFABC

Author(s): Marie E Sweet, Xihui Zhang, Hediye Erdjument-Bromage, Vikas Dubey, Himanshu Khandelia, Thomas A Neubert, Bjørn P Pedersen, David L Stokes
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.55480

Crystal structure of the potassium-importing KdpFABC membrane complex

Author(s): Ching-Shin Huang, Bjørn Panyella Pedersen, David L. Stokes
Published in: Nature, Issue 546/7660, 2017, Page(s) 681-685, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature22970

Expression strategies for structural studies of eukaryotic membrane proteins.

Author(s): Lyons JA, Shahsavar A, Paulsen PA, Pedersen BP, Nissen P.
Published in: Curr Opin Struct Biol., 2016, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2016.06.011

Initiating heavy-atom-based phasing by multi-dimensional molecular replacement.

Author(s): Pedersen BP, Gourdon P, Liu X, Karlsen JL, Nissen P.
Published in: Acta Crystallogr D Struct Biol., 2016, ISSN 2059-7983
Publisher: IUCr
DOI: 10.1107/S2059798315022482

Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides

Author(s): Khyati Kapoor, Janet S. Finer-Moore, Bjørn P. Pedersen, Laura Caboni, Andrew Waight, Roman C. Hillig, Peter Bringmann, Iring Heisler, Thomas Müller, Holger Siebeneicher, and Robert M. Stroud
Published in: Proc Natl Acad Sci U S A, 2016, ISSN 1091-6490
Publisher: PNAS
DOI: 10.1073/pnas.1603735113

Namdinator – automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps

Author(s): Rune Thomas Kidmose, Jonathan Juhl, Poul Nissen, Thomas Boesen, Jesper Lykkegaard Karlsen, Bjørn Panyella Pedersen
Published in: IUCrJ, Issue 6/4, 2019, Page(s) 526-531, ISSN 2052-2525
Publisher: International Union of Crystallography
DOI: 10.1107/s2052252519007619

The KdpFABC complex – K + transport against all odds

Author(s): Bjørn P. Pedersen, David L. Stokes, Hans-Jürgen Apell
Published in: Molecular Membrane Biology, 2019, Page(s) 1-34, ISSN 0968-7688
Publisher: Taylor & Francis
DOI: 10.1080/09687688.2019.1638977

Crystal structure of the plant symporter STP10 illuminates sugar uptake mechanism in monosaccharide transporter superfamily

Author(s): Peter Aasted Paulsen, Tânia F. Custódio, Bjørn Panyella Pedersen
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-08176-9

Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins

Author(s): Mikael B.L. Winkler, Rune T. Kidmose, Maria Szomek, Katja Thaysen, Shaun Rawson, Stephen P. Muench, Daniel Wüstner, Bjørn Panyella Pedersen
Published in: Cell, Issue 179/2, 2019, Page(s) 485-497.e18, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.08.038