Molecular basis of the cross-talk between chronic inflammation and cancer

Project Information

CrIC

Grant agreement ID: 637763

DOI 10.3030/637763

Project closed

EC signature date 24 March 2015

Start date 1 April 2015

End date 31 March 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

Publications

Peer reviewed articles (4)

Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation

Author(s): J. Guerra, A.-L. Valadao, D. Vlachakis, K. Polak, I. K. Vila, C. Taffoni, T. Prabakaran, A. S. Marriott, R. Kaczmarek, A. Houel, B. Auzemery, S. Déjardin, P. Boudinot, B. Nawrot, N. J. Jones, S. R. Paludan, S. Kossida, C. Langevin, N. Laguette
Published in: Science Advances, Issue 6/21, 2020, Page(s) eaax3333, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.aax3333

Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives

Author(s): Isabelle K. Vila, Maxence Fretaud, Dimitrios Vlachakis, Nadine Laguette, Christelle Langevin
Published in: Journal of Molecular Biology, Issue 432/20, 2020, Page(s) 5529-5543, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2020.08.016

Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production

Author(s): Christelle Brégnard, Jessica Guerra, Stéphanie Déjardin, Frank Passalacqua, Monsef Benkirane, Nadine Laguette
Published in: EBioMedicine, Issue 8, 2016, Page(s) 184-194, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2016.05.005

Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes

Author(s): Clara Taffoni, Alizée Steer, Johanna Marines, Hanane Chamma, Isabelle K. Vila, Nadine Laguette
Published in: Frontiers in Immunology, Issue 12, 2021, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2021.660560

Intellectual Property Rights

Patent (1)

STING INHIBITORS AND THEIR THERAPEUTIC USES

Application/Publication number: 20 20074785
Date: 2020-09-04