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Metabolism of DNA secondary structures and their impact on genome stability

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Publications

Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy

Author(s): Peter A. Summers, Benjamin W. Lewis, Jorge Gonzalez-Garcia, Rosa M. Porreca, Aaron H. M. Lim, Paolo Cadinu, Nerea Martin-Pintado, David J. Mann, Joshua B. Edel, Jean Baptiste Vannier, Marina K. Kuimova, Ramon Vilar
Published in: Nature Communications, 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20414-7

XPO7 is a tumor suppressor regulating p21 CIP1 -dependent senescence

Author(s): Andrew J. Innes, Bin Sun, Verena Wagner, Sharon Brookes, Domhnall McHugh, Joaquim Pombo, Rosa María Porreca, Gopuraja Dharmalingam, Santiago Vernia, Johannes Zuber, Jean-Baptiste Vannier, Ramón García-Escudero, Jesús Gil
Published in: Genes & Development, 35/5-6, 2021, Page(s) 379-391, ISSN 0890-9369
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.343269.120

TRF1 averts chromatin remodelling, recombination and replication dependent-break induced replication at mouse telomeres

Author(s): Rosa Maria Porreca, Emilia Herrera-Moyano, Eleni Skourti, Pui Pik Law, Roser Gonzalez Franco, Alex Montoya, Peter Faull, Holger Kramer, Jean-Baptiste Vannier
Published in: eLife, 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.49817

The human SKI complex prevents DNA-RNA hybrid-associated telomere instability

Author(s): Emilia Herrera-Moyano, Rosa Maria Porreca, Lepakshi Ranjha, Eleni Skourti, Roser Gonzalez-Franco, Ying Sun, Emmanouil Stylianakis, Alex Montoya, Holger Kramer, Jean-Baptiste Vannier
Published in: BioRxiv, 2021
Publisher: BioRxiv
DOI: 10.1101/2020.05.20.107144