Objective Fusarium fujikuroi (Giberella fujikuroi) is a fungus of biotechnological interest because of its use as industrial source of gibberellins, plant hormones with agricultural applications. Additionally, F. fujikuroi is able to produce carotenoids, compounds used as food additives with beneficial effects on health. Current trends favour the biotechnological production of carotenoids against chemical synthesis. Fungi are among the preferred sources for industrial carotenoids production and the study of its regulatory mechanisms is a major line of research to improve yields.The ability of F. fujikuroi to produce carotenoids and gibberellins makes this fungus a unique research model to investigate the regulatory relations between both pathways, which share their first biosynthetic steps. The group in which the applicant has reintegrated focuses its research in the regulation of carotenoid and gibberellin biosynthesis in F. fujikuroi. The project aims to investigate the carbon catabolite repression of carotenoid and gibberellin biosynthesis in F. fujikuroi. Mutants with partial deletions of gene creA will be constructed to obtain increased production of carotens and/or gibberellins. Expression of genes from both pathways will be studied and caroten production will be followed by HPLC measurement. Fields of science natural sciencesbiological sciencesmicrobiologymycologynatural sciencesbiological sciencesbiochemistrybiomoleculescarbohydratesagricultural sciencesagriculture, forestry, and fisheriesagriculturenatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymesengineering and technologyindustrial biotechnologybioprocessing technologiesfermentation Programme(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Topic(s) MOBILITY-4.1 - Marie Curie European Reintegration Grants (ERG) Call for proposal FP6-2002-MOBILITY-11 See other projects for this call Funding Scheme ERG - Marie Curie actions-European Re-integration Grants Coordinator UNIVERSIDAD DE SEVILLA Address C/ san fernando 4 Sevilla Spain See on map EU contribution € 0,00
