Beyond genotype to phenotype: how ancestor lifestyle impacts on lifespan variation in descendants

Project Information

NoisyAgeing

Grant agreement ID: 638426

DOI

10.3030/638426

Project closed

EC signature date 5 May 2015

Start date 1 June 2015

End date 30 June 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 978,00

EU contribution

€ 1 499 978,00

Coordinated by

THE BABRAHAM INSTITUTE
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Autophagy compensates for defects in mitochondrial dynamics

Author(s): Simon Haeussler, Fabian Köhler, Michael Witting, Madeleine F. Premm, Stéphane G. Rolland, Christian Fischer, Laetitia Chauve, Olivia Casanueva, Barbara Conradt
Published in: PLOS Genetics, Issue 16/3, 2020, Page(s) e1008638, ISSN 1553-7404
Publisher: PLOS
DOI: 10.1371/journal.pgen.1008638

High-Throughput Quantitative RT-PCR in Single and Bulk <em>C. elegans</em> Samples Using Nanofluidic Technology

Author(s): Laetitia Chauve, Jérémie Le Pen, Francesca Hodge, Pia Todtenhaupt, Laura Biggins, Eric A. Miska, Simon Andrews, Olivia Casanueva
Published in: Journal of Visualized Experiments, Issue 159, 2020, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/61132

Epigenetic inheritance of proteostasis and ageing

Author(s): C. Li, O. Casanueva
Published in: Essays In Biochemistry, Issue 60/2, 2016, Page(s) 191-202, ISSN 0071-1365
Publisher: Portland Press, Ltd.
DOI: 10.1042/EBC20160025

Modeling Meets Metabolomics—The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism Caenorhabditis elegans

Author(s): Michael Witting, Janna Hastings, Nicolas Rodriguez, Chintan J. Joshi, Jake P. N. Hattwell, Paul R. Ebert, Michel van Weeghel, Arwen W. Gao, Michael J. O. Wakelam, Riekelt H. Houtkooper, Abraham Mains, Nicolas Le Novère, Sean Sadykoff, Frank Schroeder, Nathan E. Lewis, Horst-Joachim Schirra, Christoph Kaleta, Olivia Casanueva
Published in: Frontiers in Molecular Biosciences, Issue 5, 2018, ISSN 2296-889X
Publisher: Frontiers SA
DOI: 10.3389/fmolb.2018.00096

Multi-Omics and Genome-Scale Modeling Reveal a Metabolic Shift During C. elegans Aging

Author(s): Janna Hastings, Abraham Mains, Bhupinder Virk, Nicolas Rodriguez, Sharlene Murdoch, Juliette Pearce, Sven Bergmann, Nicolas Le Novère, Olivia Casanueva
Published in: Frontiers in Molecular Biosciences, Issue 6, 2019, ISSN 2296-889X
Publisher: Frontiers media SA
DOI: 10.3389/fmolb.2019.00002

Neuronal XBP-1 Activates Intestinal Lysosomes to Improve Proteostasis in C. elegans

Author(s): Soudabeh Imanikia, Neşem P. Özbey, Christel Krueger, M. Olivia Casanueva, Rebecca C. Taylor
Published in: Current Biology, Issue 29/14, 2019, Page(s) 2322-2338.e7, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2019.06.031

Tyramine Acts Downstream of Neuronal XBP-1s to Coordinate Inter-tissue UPRER Activation and Behavior in C. elegans

Author(s): Neşem P. Özbey, Soudabeh Imanikia, Christel Krueger, Iris Hardege, Julia Morud, Ming Sheng, William R. Schafer, M. Olivia Casanueva, Rebecca C. Taylor
Published in: Developmental Cell, Issue 55/6, 2020, Page(s) 754-770.e6, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2020.10.024

Worm-align and Worm_CP, Two Open-Source Pipelines for Straightening and Quantification of Fluorescence Image Data Obtained from <em>Caenorhabditis elegans</em>

Author(s): Hanneke Okkenhaug, Laetitia Chauve, Fatemeh Masoudzadeh, Lars Okkenhaug, Olivia Casanueva
Published in: Journal of Visualized Experiments, Issue 159, 2020, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/61136

Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans

Author(s): Laetitia Chauve, Francesca Hodge, Sharlene Murdoch, Fatemah Masoudzadeh, Harry-Jack Mann, Andrea Lopez-Clavijo, Hanneke Okkenhaug, Greg West, Bebiana C. Sousa, Anne Segonds-Pichon, Cheryl Li, Steven Wingett, Hermine Kienberger, Karin Kleigrewe, Mario De Bono, Michael Wakelam, Olivia Casanueva
Published in: PLOS Biology, Issue 19/11, 2021, Page(s) e3001431, ISSN 1545-7885
Publisher: PLOS
DOI: 10.1371/journal.pbio.3001431