DNA end protection in Immunity and Cancer

Project Information

DNAendProtection

Grant agreement ID: 638897

DOI 10.3030/638897

Project closed

EC signature date 23 April 2015

Start date 1 September 2015

End date 30 June 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 993 421,00

EU contribution € 1 993 421,00

Coordinated by

MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
Germany

Publications

Peer reviewed articles (4)

Charting a DNA Repair Roadmap for Immunoglobulin Class Switch Recombination

Author(s): Tannishtha Saha, Devakumar Sundaravinayagam, Michela Di Virgilio
Published in: Trends in Biochemical Sciences, Issue 46/3, 2021, Page(s) 184-199, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2020.10.005

The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination

Author(s): Verónica Delgado-Benito, Daniel B. Rosen, Qiao Wang, Anna Gazumyan, Joy A. Pai, Thiago Y. Oliveira, Devakumar Sundaravinayagam, Wenzhu Zhang, Matteo Andreani, Lisa Keller, Kyong-Rim Kieffer-Kwon, Aleksandra Pękowska, Seolkyoung Jung, Madlen Driesner, Roman I. Subbotin, Rafael Casellas, Brian T. Chait, Michel C. Nussenzweig, Michela Di Virgilio
Published in: Molecular Cell, 2018, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.08.042

53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function

Author(s): Devakumar Sundaravinayagam, Ali Rahjouei, Matteo Andreani, Dagnija Tupiņa, Sandhya Balasubramanian, Tannishtha Saha, Verónica Delgado-Benito, Violeta Coralluzzo, Oliver Daumke, Michela Di Virgilio
Published in: Cell Reports, Issue 28/6, 2019, Page(s) 1389-1399.e6, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.06.035

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

Author(s): Verónica Delgado-Benito, Maria Berruezo-Llacuna, Robert Altwasser, Wiebke Winkler, Devakumar Sundaravinayagam, Sandhya Balasubramanian, Marieta Caganova, Robin Graf, Ali Rahjouei, Marie-Thérèse Henke, Madlen Driesner, Lisa Keller, Alessandro Prigione, Martin Janz, Altuna Akalin, Michela Di Virgilio
Published in: Journal of Experimental Medicine, Issue 217/10, 2020, ISSN 0022-1007
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20200137