DNA end protection in Immunity and Cancer

Project Information

DNAendProtection

Grant agreement ID: 638897

DOI

10.3030/638897

Project closed

EC signature date 23 April 2015

Start date 1 September 2015

End date 30 June 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 993 421,00

EU contribution

€ 1 993 421,00

Coordinated by

MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Charting a DNA Repair Roadmap for Immunoglobulin Class Switch Recombination

Author(s): Tannishtha Saha, Devakumar Sundaravinayagam, Michela Di Virgilio
Published in: Trends in Biochemical Sciences, Issue 46/3, 2021, Page(s) 184-199, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2020.10.005

The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination

Author(s): Verónica Delgado-Benito, Daniel B. Rosen, Qiao Wang, Anna Gazumyan, Joy A. Pai, Thiago Y. Oliveira, Devakumar Sundaravinayagam, Wenzhu Zhang, Matteo Andreani, Lisa Keller, Kyong-Rim Kieffer-Kwon, Aleksandra Pękowska, Seolkyoung Jung, Madlen Driesner, Roman I. Subbotin, Rafael Casellas, Brian T. Chait, Michel C. Nussenzweig, Michela Di Virgilio
Published in: Molecular Cell, 2018, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.08.042

53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function

Author(s): Devakumar Sundaravinayagam, Ali Rahjouei, Matteo Andreani, Dagnija Tupiņa, Sandhya Balasubramanian, Tannishtha Saha, Verónica Delgado-Benito, Violeta Coralluzzo, Oliver Daumke, Michela Di Virgilio
Published in: Cell Reports, Issue 28/6, 2019, Page(s) 1389-1399.e6, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.06.035

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

Author(s): Verónica Delgado-Benito, Maria Berruezo-Llacuna, Robert Altwasser, Wiebke Winkler, Devakumar Sundaravinayagam, Sandhya Balasubramanian, Marieta Caganova, Robin Graf, Ali Rahjouei, Marie-Thérèse Henke, Madlen Driesner, Lisa Keller, Alessandro Prigione, Martin Janz, Altuna Akalin, Michela Di Virgilio
Published in: Journal of Experimental Medicine, Issue 217/10, 2020, ISSN 0022-1007
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20200137