Quantitative developmental genetic analysis of phenotypic buffering and cryptic variation

Project Information

ROBUSTNET

Grant agreement ID: 639485

DOI 10.3030/639485

Project closed

EC signature date 14 July 2015

Start date 1 October 2015

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 499 745,00

EU contribution € 1 499 745,00

Coordinated by

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom

Publications

Peer reviewed articles (7)

Gene expression profiling of epidermal cell types in C. elegans using Targeted DamID

Author(s): Dimitris Katsanos, Mar Ferrando-Marco, Iqrah Razzaq, Gabriel Aughey, Tony D. Southall, Michalis Barkoulas
Published in: Development, Issue 148/17, 2021, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.199452

A role for the fusogen eff-1 in epidermal stem cell number robustness in Caenorhabditis elegans

Author(s): Sneha L. Koneru, Fu Xiang Quah, Ritobrata Ghose, Mark Hintze, Nicola Gritti, Jeroen Sebastiaan van Zon, Michalis Barkoulas
Published in: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-88500-4

Cryptic genetic variation in a heat shock protein modifies the outcome of a mutation affecting epidermal stem cell development in C. elegans

Author(s): Sneha L. Koneru, Mark Hintze, Dimitris Katsanos, Michalis Barkoulas
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-23567-1

Natural Infection of C. elegans by an Oomycete Reveals a New Pathogen-Specific Immune Response

Author(s): Guled A. Osman, Michael K. Fasseas, Sneha L. Koneru, Clara L. Essmann, Kyros Kyrou, Mandayam A. Srinivasan, Gaotian Zhang, Peter Sarkies, Marie-Anne Félix, Michalis Barkoulas
Published in: Current Biology, Issue 28/4, 2018, Page(s) 640-648.e5, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2018.01.029

Stochastic loss and gain of symmetric divisions in the C. elegans epidermis perturbs robustness of stem cell number

Author(s): Dimitris Katsanos, Sneha L. Koneru, Lamia Mestek Boukhibar, Nicola Gritti, Ritobrata Ghose, Peter J. Appleford, Maria Doitsidou, Alison Woollard, Jeroen S. van Zon, Richard J. Poole, Michalis Barkoulas
Published in: PLOS Biology, Issue 15/11, 2017, Page(s) e2002429, ISSN 1545-7885
Publisher: PLOS
DOI: 10.1371/journal.pbio.2002429

A Cell Fate Switch in the Caenorhabditis elegans Seam Cell Lineage Occurs Through Modulation of the Wnt Asymmetry Pathway in Response to Temperature Increase

Author(s): Mark Hintze, Sneha L. Koneru, Sophie P. R. Gilbert, Dimitris Katsanos, Julien Lambert, Michalis Barkoulas
Published in: Genetics, Issue 214/4, 2020, Page(s) 927-939, ISSN 0016-6731
Publisher: Genetics Society of America
DOI: 10.1534/genetics.119.302896

Phenotypic Robustness of Epidermal Stem Cell Number in C. elegans Is Modulated by the Activity of the Conserved N-acetyltransferase nath-10/NAT10

Author(s): Mark Hintze, Dimitris Katsanos, Vahid Shahrezaei, Michalis Barkoulas
Published in: Frontiers in Cell and Developmental Biology, Issue 9, 2021, ISSN 2296-634X
Publisher: Frontiers
DOI: 10.3389/fcell.2021.640856