Transgenerational transmission of maternal childhood trauma and its sequelae – Altered maternal physiology during pregnancy and implications for newborn neurodevelopment

Project Information

TransCTNeurodev

Grant agreement ID: 639766

DOI 10.3030/639766

Project closed

EC signature date 9 September 2015

Start date 1 November 2015

End date 31 December 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 496 132,50

EU contribution € 1 496 132,50

Coordinated by

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany

Publications

Peer reviewed articles (15)

Sleep across the first year of life is prospectively associated with brain volume in 12-months old infants

Author(s): Katharina Pittner; Jerod Rasmussen; Miranda M. Lim; John H. Gilmore; Martin Styner; Sonja Entringer; Pathik D. Wadhwa; Claudia Buss
Published in: Crossref, Issue 1, 2023, ISSN 2451-9944
Publisher: Elsevier
DOI: 10.1016/j.nbscr.2023.100091

The Association between History of Prenatal Loss and Maternal Psychological State in a Subsequent Pregnancy: an Ecological Momentary Assessment (EMA) Study.

Author(s): Lazarides C, Moog N, Verner G, Voelkle MC, Henrich W, Heim CM, Braun T, Wadhwa PD, Buss C, Entringer S.
Published in: Psychological Medicine, 2021, ISSN 0033-2917
Publisher: Cambridge University Press
DOI: 10.1017/s0033291721002221

Exposure to Childhood Maltreatment and Systemic Inflammation across Pregnancy: the Moderating Role of Depressive Symptomatology

Author(s): Kleih T, Entringer S, Scholaske L, Kathmann N, DePunder K, Heim CM, Wadhwa PD, Buss C
Published in: Brain, Behavior and Immunity, 2022, ISSN 0889-1591
Publisher: Academic Press
DOI: 10.1016/j.bbi.2022.02.004

Transmission of the Adverse Consequences of Childhood Maltreatment across Generations: Focus on Gestational Biology.

Author(s): Moog NK, Heim CM, Entringer S, Simhan HN, Wadhwa PD, Buss C
Published in: Pharmacology Biochemistry and Behavior, 2022, ISSN 0091-3057
Publisher: Ankho International, Ltd.
DOI: 10.1016/j.pbb.2022.173372

Maternal Inflammation during Pregnancy and Offspring Brain Development: the Role of Mitochondria.

Author(s): Gyllenhammer LE, Rasmussen J, Bertele N, Halbing N, Entringer S, Wadhwa PD, Buss C.
Published in: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2021, ISSN 2451-9022
Publisher: Elsevier
DOI: 10.1016/j.bpsc.2021.11.003

Maternal exposure to childhood maltreatment and adverse birth outcomes

Author(s): Lauren S. Keenan-Devlin; Ann E. B. Borders; Alexa Freedman; Gregory E. Miller; William Grobman; Sonja Entringer; Hyagriv Simhan; Pathik Wadhwa; Claudia Buss
Published in: Scientific reports, vol 13, iss 1, Issue 2, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-36831-9

How Many Are Too Much? Clinical and Epidemiological Considerations for the Era of Poly–Pre- and Postnatal Exposures Relevant for the Developing Brain

Author(s): Claudia, Buss; Jon, Genuneit
Published in: Crossref, Issue 1, 2023, ISSN 1873-2402
Publisher: Elsevier
DOI: 10.1016/j.biopsych.2022.06.025

Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders

Author(s): Alex, Ann M; Buss, Claudia; Davis, Elysia Poggi; de los Campos, Gustavo; Donald, Kirsten A; Fair, Damien A; Gaab, Nadine; Gao, Wei; Gilmore, John H; Girault, Jessica B; Grewen, Karen; Groenewold, Nynke A; Hankin, Benjamin L; Ipser, Jonathan; Kapoor, Shreya; Kim, Pilyoung; Lin, Weili; Luo, Shan; Norton, Elizabeth S; O’Connor, Thomas G; Piven, Joseph; Qiu, Anqi; Rasmussen, Jerod M; Skeide, Michael
Published in: Biological Psychiatry, vol 93, iss 10, Issue 1, 2023, ISSN 1873-2402
Publisher: Elsevier

Neonatal brain volume as a marker of differential susceptibility to parenting quality and its association with neurodevelopment across early childhood

Author(s): Nolvi S, Rasmussen JM, Graham AM, Gilmore JH, Styner M, Fair DA, Entringer S, Wadhwa PD, Buss C.
Published in: Developmental Cognitive Neuroscience, 2020, ISSN 1878-9293
Publisher: Elsevier BV
DOI: 10.1016/j.dcn.2020.100826

Hippocampal Volume Moderates the Effects of Early Enrichment on Cognitive Development

Author(s): Overfeld J, Entringer S, Rasmussen JM, Heim CM, Styner M, Gilmore JH, Wadhwa PD, Buss C.
Published in: Developmental Cognitive Neuroscience, Issue 45:100820, 2020, ISSN 1878-9293
Publisher: Elsevier BV
DOI: 10.1016/j.dcn.2020.100820

A Role of Oxytocin Receptor Gene Brain Tissue Expression Quantitative Trait Locus rs237895 in the Intergenerational Transmission of the Effects of Maternal Childhood Maltreatment

Author(s): Philipp Toepfer, Kieran J. O'Donnell, Sonja Entringer, Christine M. Heim, David T.S. Lin, Julia L. MacIsaac, Michael S. Kobor, Michael J. Meaney, Nadine Provençal, Elisabeth B. Binder, Pathik D. Wadhwa, Claudia Buss
Published in: Journal of the American Academy of Child & Adolescent Psychiatry, 2019, ISSN 0890-8567
Publisher: Elsevier BV
DOI: 10.1016/j.jaac.2019.03.006

Translating basic research knowledge on the biological embedding of early-life stress into novel approaches for the developmental programming of lifelong health

Author(s): Christine M. Heim, Sonja Entringer, Claudia Buss
Published in: Psychoneuroendocrinology, 2018, ISSN 0306-4530
Publisher: Pergamon Press
DOI: 10.1016/j.psyneuen.2018.12.011

Prenatal Immune and Endocrine Modulators of Offspring's Brain Development and Cognitive Functions Later in Life.

Author(s): Steven Schepanski; Steven Schepanski; Claudia Buss; Claudia Buss; Ileana L. Hanganu-Opatz; Petra C. Arck
Published in: Frontiers in Immunology, Issue 1, 2018, ISSN 1664-3224
Publisher: Lausanne: Frontiers Media S.A., 2010-
DOI: 10.3389/fimmu.2018.02186

Prospective Association of Maternal Psychosocial Stress in Pregnancy with Newborn Hippocampal Volume and Implications for Infant Social-emotional Development.

Author(s): Moog NK, Nolvi S, Kleih TS, Styner M, Gilmore JH, Rasmussen JM, Heim CM, Entringer S, Wadhwa PD, Buss C
Published in: Neurobiology of Stress, 2021, ISSN 2352-2895
Publisher: Elsevier BV
DOI: 10.1016/j.ynstr.2021.100368

Biochemical Clusters Predict Mortality and Inability to Work 10 Years Later.

Author(s): Bertele N, Karabatsiakis A, Talmon A, Buss C.
Published in: Brain Behavior and Immunity - Health, 2022, ISSN 2666-3546
Publisher: New York: Elsevier Inc.
DOI: 10.1016/j.bbih.2022.100432