Metabolic and Genetic Regulation of Ageing

Project Information

MetAGEn

Grant agreement ID: 640254

DOI

10.3030/640254

Project closed

EC signature date 23 July 2015

Start date 1 August 2015

End date 31 July 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis

Author(s): Sabine Ruegenberg, Moritz Horn, Christian Pichlo, Kira Allmeroth, Ulrich Baumann, Martin S. Denzel
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-14524-5

Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response

Author(s): Moritz Horn, Sarah I. Denzel, Balaji Srinivasan, Kira Allmeroth, Isabelle Schiffer, Vignesh Karthikaisamy, Stephan Miethe, Peter Breuer, Adam Antebi, Martin S. Denzel
Published in: iScience, Issue 23/3, 2020, Page(s) 100887, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2020.100887

Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics

Author(s): Martin S. Denzel, Louis R. Lapierre, Hildegard I.D. Mack
Published in: Mechanisms of Ageing and Development, Issue 177, 2019, Page(s) 4-21, ISSN 0047-6374
Publisher: Elsevier BV
DOI: 10.1016/j.mad.2018.08.001

Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells

Author(s): Moritz Horn, Virginia Kroef, Kira Allmeroth, Nicole Schuller, Stephan Miethe, Martin Peifer, Josef M. Penninger, Ulrich Elling, Martin S. Denzel
Published in: Oncotarget, Issue 9/11, 2018, ISSN 1949-2553
Publisher: Impact Journals
DOI: 10.18632/oncotarget.24305

Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma

Author(s): Kira Allmeroth, Moritz Horn, Virginia Kroef, Stephan Miethe, Roman-Ulrich Müller, Martin S. Denzel
Published in: Leukemia, 2020, ISSN 0887-6924
Publisher: Nature Publishing Group
DOI: 10.1038/s41375-020-0989-4