Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis
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Author(s):
Sabine Ruegenberg, Moritz Horn, Christian Pichlo, Kira Allmeroth, Ulrich Baumann, Martin S. Denzel
Published in:
Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher:
Nature Publishing Group
DOI:
10.1038/s41467-020-14524-5
Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response
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Author(s):
Moritz Horn, Sarah I. Denzel, Balaji Srinivasan, Kira Allmeroth, Isabelle Schiffer, Vignesh Karthikaisamy, Stephan Miethe, Peter Breuer, Adam Antebi, Martin S. Denzel
Published in:
iScience, Issue 23/3, 2020, Page(s) 100887, ISSN 2589-0042
Publisher:
Cell Press
DOI:
10.1016/j.isci.2020.100887
Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics
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Author(s):
Martin S. Denzel, Louis R. Lapierre, Hildegard I.D. Mack
Published in:
Mechanisms of Ageing and Development, Issue 177, 2019, Page(s) 4-21, ISSN 0047-6374
Publisher:
Elsevier BV
DOI:
10.1016/j.mad.2018.08.001
Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells
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Author(s):
Moritz Horn, Virginia Kroef, Kira Allmeroth, Nicole Schuller, Stephan Miethe, Martin Peifer, Josef M. Penninger, Ulrich Elling, Martin S. Denzel
Published in:
Oncotarget, Issue 9/11, 2018, ISSN 1949-2553
Publisher:
Impact Journals
DOI:
10.18632/oncotarget.24305
Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma
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Author(s):
Kira Allmeroth, Moritz Horn, Virginia Kroef, Stephan Miethe, Roman-Ulrich Müller, Martin S. Denzel
Published in:
Leukemia, 2020, ISSN 0887-6924
Publisher:
Nature Publishing Group
DOI:
10.1038/s41375-020-0989-4
