Molecularly defined models of human childhood brain tumors

Project Information

Medulloblastoma

Grant agreement ID: 640275

DOI

10.3030/640275

Project closed

EC signature date 23 April 2015

Start date 1 May 2015

End date 30 April 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 497 059,00

EU contribution

€ 1 497 059,00

Coordinated by

UPPSALA UNIVERSITET
Sweden

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Modeling and Targeting MYC Genes in Childhood Brain Tumors

Author(s): Sonja Hutter, Sara Bolin, Holger Weishaupt, Fredrik Swartling
Published in: Genes, Issue 8/12, 2017, Page(s) 107, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes8040107

Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence

Author(s): Aldwin Suryo Rahmanto, Fredrik J. Swartling, Olle Sangfelt
Published in: Molecular & Cellular Oncology, Issue 4/1, 2016, Page(s) e1252871, ISSN 2372-3556
Publisher: Taylor and Francis
DOI: 10.1080/23723556.2016.1252871

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

Author(s): Aldwin Suryo Rahmanto, Vasil Savov, Andrä Brunner, Sara Bolin, Holger Weishaupt, Alena Malyukova, Gabriela Rosén, Matko Čančer, Sonja Hutter, Anders Sundström, Daisuke Kawauchi, David TW Jones, Charles Spruck, Michael D Taylor, Yoon‐Jae Cho, Stefan M Pfister, Marcel Kool, Andrey Korshunov, Fredrik J Swartling, Olle Sangfelt
Published in: The EMBO Journal, Issue 35/20, 2016, Page(s) 2192-2212, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.201693889

Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes

Author(s): Holger Weishaupt, Patrik Johansson, Anders Sundström, Zelmina Lubovac-Pilav, Björn Olsson, Sven Nelander, Fredrik J Swartling
Published in: Bioinformatics, Issue 35/18, 2019, Page(s) 3357-3364, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/btz066

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Author(s): Matko Čančer, Sonja Hutter, Karl O. Holmberg, Gabriela Rosén, Anders Sundström, Jignesh Tailor, Tobias Bergström, Alexandra Garancher, Magnus Essand, Robert J. Wechsler-Reya, Anna Falk, Holger Weishaupt, Fredrik J. Swartling
Published in: Cell Stem Cell, Issue 25, 2019, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2019.10.005