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Molecularly defined models of human childhood brain tumors


Modeling and Targeting MYC Genes in Childhood Brain Tumors

Author(s): Sonja Hutter, Sara Bolin, Holger Weishaupt, Fredrik Swartling
Published in: Genes, Issue 8/12, 2017, Page(s) 107, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes8040107

Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence

Author(s): Aldwin Suryo Rahmanto, Fredrik J. Swartling, Olle Sangfelt
Published in: Molecular & Cellular Oncology, Issue 4/1, 2016, Page(s) e1252871, ISSN 2372-3556
Publisher: Taylor and Francis
DOI: 10.1080/23723556.2016.1252871

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

Author(s): Aldwin Suryo Rahmanto, Vasil Savov, Andrä Brunner, Sara Bolin, Holger Weishaupt, Alena Malyukova, Gabriela Rosén, Matko Čančer, Sonja Hutter, Anders Sundström, Daisuke Kawauchi, David TW Jones, Charles Spruck, Michael D Taylor, Yoon‐Jae Cho, Stefan M Pfister, Marcel Kool, Andrey Korshunov, Fredrik J Swartling, Olle Sangfelt
Published in: The EMBO Journal, Issue 35/20, 2016, Page(s) 2192-2212, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.201693889

Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes

Author(s): Holger Weishaupt, Patrik Johansson, Anders Sundström, Zelmina Lubovac-Pilav, Björn Olsson, Sven Nelander, Fredrik J Swartling
Published in: Bioinformatics, Issue 35/18, 2019, Page(s) 3357-3364, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/btz066

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

Author(s): Matko Čančer, Sonja Hutter, Karl O. Holmberg, Gabriela Rosén, Anders Sundström, Jignesh Tailor, Tobias Bergström, Alexandra Garancher, Magnus Essand, Robert J. Wechsler-Reya, Anna Falk, Holger Weishaupt, Fredrik J. Swartling
Published in: Cell Stem Cell, Issue 25, 2019, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2019.10.005

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