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Zinc finger gene therapy in the brain for treating Huntington's disease

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Publications

A shared mechanism of muscle wasting in cancer and Huntington’s disease

Author(s): Michal Mielcarek, Mark Isalan
Published in: Clinical and Translational Medicine, Issue 4/1, 2015, ISSN 2001-1326
DOI: 10.1186/s40169-015-0076-z

Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice

Author(s): Carmen Agustín-Pavón, Michal Mielcarek, Mireia Garriga-Canut, Mark Isalan
Published in: Molecular Neurodegeneration, Issue 11/1, 2016, ISSN 1750-1326
DOI: 10.1186/s13024-016-0128-x

Huntington's disease is a multi-system disorder


Published in: ISSN 2167-5511
DOI: 10.1080/21675511.2015.1058464