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EUROPOL

Objective

NMR and MRI play unique roles in contemporary Science, from Physics, Chemistry and Biology, to clinical research and diagnosis. Despite its irreplaceable role, further progress in NMR and MRI is hampered by sensitivities that are much lower than those of alternatives such as mass-spec, or PET. The prospects of solving this problem by “bigger machines” are uncertain and of poor return, given the high maturity already achieved by NMR/MRI. This ETN challenges this status from an untapped perspective, combining NMR/MRI with nuclear hyperpolarization eliciting signals that surpass those currently available by up to 50,000x. Focus is placed on two particular approaches, dynamic nuclear polarization and para-hydrogen-driven polarization, exhibiting the highest potential for biophysical, metabolomic, pre-clinical and clinical research. To maximize these “supersignals” we assembled leading experts in the physics and engineering of magnetic resonance, in the synthetic chemistry essential for the success of these methods, in the uses of NMR to structural/cell biology, and in preclinical and clinical MRI applications. Guiding this assembling is the conception that only by teaming together key areas of expertise, can hyperpolarisation’s promises be realized. In addition to fostering synergies among experts from academia and industry, EUROPOL will provide frontier training for ESRs in all the topics underlying the advancement of MR. This will include advanced physics, new instruments and forms of exploiting NMR/MRI’s hyperpolarisation, biophysical NMR, screening of healthy and diseased metabolomes, expanded portfolios of substrates to be targeted by in vivo MR, ancillary in cell and system biology explorations clarifying the nature of the metabolic phenomena, and in vivo hyperpolarisation strategies in MRI. This ETN is unparalleled in scope, breadth and potential for synergies.

Call for proposal

H2020-MSCA-ITN-2014
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

THE UNIVERSITY OF BIRMINGHAM
Address
Edgbaston
B15 2TT Birmingham
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 546 575,76

Participants (11)

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 273 287,88
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
EU contribution
€ 273 287,88
Address
University Park
NG7 2RD Nottingham
Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF YORK
United Kingdom
EU contribution
€ 273 287,88
Address
Heslington
YO10 5DD York North Yorkshire
Activity type
Higher or Secondary Education Establishments
WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 780 901,56
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments
UNIVERSITE D'AIX MARSEILLE
France
EU contribution
€ 262 875,60
Address
Boulevard Charles Livon 58
13284 Marseille
Activity type
Higher or Secondary Education Establishments
DANMARKS TEKNISKE UNIVERSITET
Denmark
EU contribution
€ 290 081,88
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Germany
EU contribution
€ 498 432,96
Address
Theodor W Adorno Platz 1
60323 Frankfurt Am Main
Activity type
Higher or Secondary Education Establishments
OXFORD INSTRUMENTS INDUSTRIAL PRODUCTS LIMITED

Participation ended

United Kingdom
EU contribution
€ 0
Address
Tubney Woods
OX13 5QX Abingdon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITAETSKLINIKUM FREIBURG
Germany
EU contribution
€ 498 432,96
Address
Hugstetter Strasse 49
79106 Freiburg
Activity type
Higher or Secondary Education Establishments
Rotem Industries Ltd.

Participation ended

Israel
EU contribution
€ 0
Address
Rotem Industrial Park, Mishor Yamin D.n Arava
86800 Mishor Yamin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CORTECNET
France
EU contribution
€ 262 875,60
Address
15/17 Rue Des Tilleuls Les Espaces Des Vergers
78960 Voisins Le Bretonneux
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)

Partners (4)

UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES.
France
Address
Avenue De Paris 55
78035 Versailles
Activity type
Higher or Secondary Education Establishments
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland
Address
Batiment Ce 3316 Station 1
1015 Lausanne
Activity type
Higher or Secondary Education Establishments
BRUKER BIOSPIN GMBH
Germany
Address
Am Silberstreifen
76287 Rheinstetten
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
GE Global Research
Germany
Address

München
Activity type
Other