Skip to main content

Integrated Spectrometers for Spectral Tissue Sensing

Objective

Image-guided needle procedures - such as taking biopsies in screening cancerous tumours - are becoming increasingly important in clinical practice. Today, physicians are severely hampered by the lack of precision in positioning the needle tip. Real-time tissue-characterization feedback at the needle tip during these procedures can significantly improve the outcome of diagnosis and treatment, and reduce the cost of oncology treatment. Spectral tissue sensing using photonic needles has the promise to be a valuable diagnostic tool for screening tumours, as shown by several clinical trials. However, for widespread adoption the cost and size of these photonic needle systems - in particular the spectrometer console - needs to be improved dramatically. The realization of a low-cost miniature system is limited by three key challenges:
• Broadband (VIS+NIR) illumination
• Broadband (VIS+NIR) sensitivity
• Integration of the system
InSPECT will address these challenges by developing and integrating photonic building blocks for low-cost miniaturized spectral tissue sensing devices. This involves the realization of a miniature broadband (400-1700 nm) solid-state light source, based on phosphor and quantum-dot converted LEDs, and the realization of a miniature low-cost integrated VIS+NIR spectrometer. For the spectrometer integration we will follow 2 approaches:
• The micro-spectrometer, a moderate risk approach based on the miniaturisation and monolithic integration of diffractive dispersive elements and VIS+NIR photo-detectors in a small volume (cubic inch) device, and
• The nano-spectrometer, a higher risk approach in which the spectrometer function is realized in a photonic integrated circuit (PIC) based on transparent SiO/SiN waveguide technology.
This is a unique, novel, and timely approach to realize the key photonics building blocks for low-cost miniature spectrometers that will drive the adoption of spectral sensing in applications that were not accessible before.

Field of science

  • /medical and health sciences/clinical medicine/oncology

Call for proposal

H2020-ICT-2014-1
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

PHILIPS ELECTRONICS NEDERLAND BV
Address
High Tech Campus 52
5656 AG Eindhoven
Netherlands
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 1 011 583

Participants (8)

AVANTES BV
Netherlands
EU contribution
€ 247 766
Address
Oude Apeldoornseweg 28
7333 NS Apeldoorn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VRIJE UNIVERSITEIT BRUSSEL
Belgium
EU contribution
€ 384 875
Address
Pleinlaan 2
1050 Brussel
Activity type
Higher or Secondary Education Establishments
XENICS NV
Belgium
EU contribution
€ 542 110
Address
Ambachtenlaan 44
3001 Leuven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ANTERYON BV
Netherlands
EU contribution
€ 287 265
Address
Zwaanstraat 2A
5651 CA Eindhoven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LIONIX INTERNATIONAL BV
Netherlands
EU contribution
€ 689 250
Address
Hengelosestraat 500
7521 AN Enschede
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 540 861
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
AIFOTEC AG
Germany
EU contribution
€ 195 875
Address
Holzmarkt 5
07743 Jena
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PHILIPS MEDICAL SYSTEMS NEDERLAND BV
Netherlands
EU contribution
€ 243 875
Address
Veenpluis 6
5684 PC Best
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)