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Integrated Spectrometers for Spectral Tissue Sensing

Objective

Image-guided needle procedures - such as taking biopsies in screening cancerous tumours - are becoming increasingly important in clinical practice. Today, physicians are severely hampered by the lack of precision in positioning the needle tip. Real-time tissue-characterization feedback at the needle tip during these procedures can significantly improve the outcome of diagnosis and treatment, and reduce the cost of oncology treatment. Spectral tissue sensing using photonic needles has the promise to be a valuable diagnostic tool for screening tumours, as shown by several clinical trials. However, for widespread adoption the cost and size of these photonic needle systems - in particular the spectrometer console - needs to be improved dramatically. The realization of a low-cost miniature system is limited by three key challenges:
• Broadband (VIS+NIR) illumination
• Broadband (VIS+NIR) sensitivity
• Integration of the system
InSPECT will address these challenges by developing and integrating photonic building blocks for low-cost miniaturized spectral tissue sensing devices. This involves the realization of a miniature broadband (400-1700 nm) solid-state light source, based on phosphor and quantum-dot converted LEDs, and the realization of a miniature low-cost integrated VIS+NIR spectrometer. For the spectrometer integration we will follow 2 approaches:
• The micro-spectrometer, a moderate risk approach based on the miniaturisation and monolithic integration of diffractive dispersive elements and VIS+NIR photo-detectors in a small volume (cubic inch) device, and
• The nano-spectrometer, a higher risk approach in which the spectrometer function is realized in a photonic integrated circuit (PIC) based on transparent SiO/SiN waveguide technology.
This is a unique, novel, and timely approach to realize the key photonics building blocks for low-cost miniature spectrometers that will drive the adoption of spectral sensing in applications that were not accessible before.

Call for proposal

H2020-ICT-2014

See other projects for this call

Sub call

H2020-ICT-2014-1

Coordinator

PHILIPS ELECTRONICS NEDERLAND BV
Net EU contribution
€ 1 011 583,00
Address
High Tech Campus 52
5656 AG Eindhoven
Netherlands

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Region
Noord-Brabant Zuidoost-Noord-Brabant
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,75

Participants (9)

AVANTES BV
Netherlands
Net EU contribution
€ 247 766,00
Address
Oude Apeldoornseweg 28
7333 NS Apeldoorn

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Oost-Nederland Gelderland Veluwe
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,25
VRIJE UNIVERSITEIT BRUSSEL
Belgium
Net EU contribution
€ 384 875,00
Address
Pleinlaan 2
1050 Brussel

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
XENICS NV
Belgium
Net EU contribution
€ 542 110,00
Address
Ambachtenlaan 44
3001 Leuven

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
ANTERYON BV
Netherlands
Net EU contribution
€ 287 265,00
Address
Zwaanstraat 2a
5651 CA Eindhoven

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Noord-Brabant Zuidoost-Noord-Brabant
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
LIONIX INTERNATIONAL BV
Netherlands
Net EU contribution
€ 689 250,00
Address
Hengelosestraat 500
7521 AN Enschede

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Oost-Nederland Overijssel Twente
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

LIONIX INTERNATIONAL BV

Participation ended

Netherlands
Net EU contribution
€ 0,00
Address
Hengelosestraat 500
7521 AN Enschede
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Oost-Nederland Overijssel Twente
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany
Net EU contribution
€ 540 861,00
Address
Hansastrasse 27c
80686 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 0,25
AIFOTEC AG
Germany
Net EU contribution
€ 195 875,00
Address
Holzmarkt 5
07743 Jena

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Thüringen Thüringen Jena, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
PHILIPS MEDICAL SYSTEMS NEDERLAND BV
Netherlands
Net EU contribution
€ 243 875,00
Address
Veenpluis 6
5684 PC Best

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Region
Noord-Brabant Zuidoost-Noord-Brabant
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00