Tubular Supramolecular Polymers: A new class of therapeutic polymers

Project Information

TUSUPO

Grant agreement ID: 647106

DOI 10.3030/647106

Project closed

EC signature date 25 March 2015

Start date 1 July 2015

End date 30 June 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 692 376,00

EU contribution € 1 692 376,00

Coordinated by

UNIVERSITY OF WARWICK
United Kingdom

Publications

Peer reviewed articles (18)

Fluorinated nanotubes: synthesis and self-assembly of cyclic peptide–poly(vinylidene fluoride) conjugates

Author(s): Enrique Folgado, Qiao Song, Sebastien Perrier, Vincent Ladmiral, Mona Semsarilar
Published in: Polymer Chemistry, Issue 12/29, 2021, Page(s) 4235-4243, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1py00355k

Comparative Study of the Cellular Uptake and Intracellular Behavior of a Library of Cyclic Peptide–Polymer Nanotubes with Different Self-Assembling Properties

Author(s): Sean H. Ellacott, Carlos Sanchez-Cano, Edward D.H. Mansfield, Julia Y. Rho, Ji-Inn Song, Raoul Peltier, Sébastien Perrier
Published in: Biomacromolecules, Issue 22/2, 2021, Page(s) 710-722, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.0c01512

Molecular Self-Assembly and Supramolecular Chemistry of Cyclic Peptides

Author(s): Qiao Song, Zihe Cheng, Maria Kariuki, Stephen C. L. Hall, Sophie K. Hill, Julia Y. Rho, Sébastien Perrier
Published in: Chemical Reviews, 2021, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.0c01291

Probing the Dynamic Nature of Self-Assembling Cyclic Peptide-Polymer Nanotubes in Solution and in Mammalian Cells

Author(s): Julia Y. Rho, Johannes C. Brendel, Liam R. MacFarlane, Edward D. H. Mansfield, Raoul Peltier, Sarah Rogers, Matthias Hartlieb, Sébastien Perrier
Published in: Advanced Functional Materials, 2017, Page(s) 1704569, ISSN 1616-301X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201704569

pH-Responsive, Amphiphilic Core–Shell Supramolecular Polymer Brushes from Cyclic Peptide–Polymer Conjugates

Author(s): Sophie C. Larnaudie, Johannes C. Brendel, Katrina A. Jolliffe, Sébastien Perrier
Published in: ACS Macro Letters, Issue 6/12, 2017, Page(s) 1347-1351, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00728

Cyclic Peptide–Polymer Nanotubes as Efficient and Highly Potent Drug Delivery Systems for Organometallic Anticancer Complexes

Author(s): Sophie C. Larnaudie, Johannes C. Brendel, Isolda Romero-Canelón, Carlos Sanchez-Cano, Sylvain Catrouillet, Joaquin Sanchis, James P. C. Coverdale, Ji-Inn Song, Abraha Habtemariam, Peter J. Sadler, Katrina A. Jolliffe, Sébastien Perrier
Published in: Biomacromolecules, Issue 19/1, 2017, Page(s) 239-247, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.7b01491

Tunable Length of Cyclic Peptide–Polymer Conjugate Self-Assemblies in Water

Author(s): Sylvain Catrouillet, Johannes C. Brendel, Sophie Larnaudie, Tammie Barlow, Katrina A. Jolliffe, Sébastien Perrier
Published in: ACS Macro Letters, Issue 5/10, 2016, Page(s) 1119-1123, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.6b00586

Imaging Proton Transport in Giant Vesicles through Cyclic Peptide-Polymer Conjugate Nanotube Transmembrane Ion Channels

Author(s): Jason G. Binfield, Johannes C. Brendel, Neil R. Cameron, Ahmed M. Eissa, Sébastien Perrier
Published in: Macromolecular Rapid Communications, 2018, Page(s) 1700831, ISSN 1022-1336
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/marc.201700831

Systematic study of the structural parameters affecting the self-assembly of cyclic peptide–poly(ethylene glycol) conjugates

Author(s): Edward D. H. Mansfield, Matthias Hartlieb, Sylvain Catrouillet, Julia Y. Rho, Sophie C. Larnaudie, Sarah E. Rogers, Joaquin Sanchis, Johannes C. Brendel, Sébastien Perrier
Published in: Soft Matter, Issue 14/30, 2018, Page(s) 6320-6326, ISSN 1744-683X
Publisher: Royal Society of Chemistry
DOI: 10.1039/C8SM01133H

Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution

Author(s): Sophie C. Larnaudie, Joaquin Sanchis, Tri-Hung Nguyen, Raoul Peltier, Sylvain Catrouillet, Johannes C. Brendel, Christopher J.H. Porter, Katrina A. Jolliffe, Sébastien Perrier
Published in: Biomaterials, Issue 178, 2018, Page(s) 570-582, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2018.03.047

Influence of block versus random monomer distribution on the cellular uptake of hydrophilic copolymers

Author(s): Moraes, J.; Peltier, R.; Gody, G.; Blum, M.; Recalcati, S.; Klok, H.-H.; Perrier, S.
Published in: ACS Macro Lett, 2016, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.6b00652

Secondary Self-Assembly of Supramolecular Nanotubes into Tubisomes and Their Activity on Cells

Author(s): Johannes C. Brendel, Joaquin Sanchis, Sylvain Catrouillet, Ewa Czuba, Moore Z. Chen, Benjamin M. Long, Cameron Nowell, Angus Johnston, Katrina A. Jolliffe, Sébastien Perrier
Published in: Angewandte Chemie International Edition, Issue 57/51, 2018, Page(s) 16678-16682, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201808543

Pyridyl Disulfide Reaction Chemistry: An Efficient Strategy toward Redox-Responsive Cyclic Peptide–Polymer Conjugates

Author(s): Qiao Song, Jie Yang, Stephen C. L. Hall, Pratik Gurnani, Sébastien Perrier
Published in: ACS Macro Letters, Issue 8/10, 2019, Page(s) 1347-1352, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.9b00538

Hydrogel and Organogel Formation by Hierarchical Self-Assembly of Cyclic Peptides Nanotubes

Author(s): Huda Shaikh, Julia Y. Rho, Laura J. Macdougall, Pratik Gurnani, Andrew M. Lunn, Jie Yang, Steve Huband, Edward D. H. Mansfield, Raoul Peltier, Sebastien Perrier
Published in: Chemistry - A European Journal, Issue 24/71, 2018, Page(s) 19066-19074, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201804576

Dual self-assembly of supramolecular peptide nanotubes to provide stabilisation in water

Author(s): Julia Y. Rho, Henry Cox, Edward D. H. Mansfield, Sean H. Ellacott, Raoul Peltier, Johannes C. Brendel, Matthias Hartlieb, Thomas A. Waigh, Sébastien Perrier
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12586-8

Stimuli-responsive membrane activity of cyclic-peptide–polymer conjugates

Author(s): Matthias Hartlieb, Sylvain Catrouillet, Agnès Kuroki, Carlos Sanchez-Cano, Raoul Peltier, Sébastien Perrier
Published in: Chemical Science, Issue 10/21, 2019, Page(s) 5476-5483, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9sc00756c

Hierarchical Self‐Assembled Photo‐Responsive Tubisomes from a Cyclic Peptide‐Bridged Amphiphilic Block Copolymer

Author(s): Jie Yang, Ji‐Inn Song, Qiao Song, Julia Y. Rho, Edward D. H. Mansfield, Stephen C. L. Hall, Megan Sambrook, Feihe Huang, Sébastien Perrier
Published in: Angewandte Chemie International Edition, Issue 59/23, 2020, Page(s) 8860-8863, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201916111

Tubular supramolecular alternating copolymers fabricated by cyclic peptide–polymer conjugates

Author(s): Qiao Song, Andrew Kerr, Jie Yang, Stephen C. L. Hall, Sébastien Perrier
Published in: Chemical Science, Issue 12/26, 2021, Page(s) 9096-9103, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1sc02389f