PROSTHETIC VALVE BIOACTIVE SURFACE COATING TO REDUCE THE PREVALENCE OF THROMBOSIS

Project Information

PV-COAT

Grant agreement ID: 647197

DOI 10.3030/647197

Project closed

EC signature date 18 May 2015

Start date 1 September 2015

End date 28 February 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 367 055,00

EU contribution € 2 367 055,00

Coordinated by

UNIVERSITE DE LIEGE
Belgium

Publications

Peer reviewed articles (14)

Antibacterial Activity of Ticagrelor in Conventional Antiplatelet Dosages Against Antibiotic-Resistant Gram-Positive Bacteria

Author(s): Patrizio Lancellotti, Lucia Musumeci, Nicolas Jacques, Laurence Servais, Eric Goffin, Bernard Pirotte, Cécile Oury
Published in: JAMA Cardiology, Issue 4/6, 2019, Page(s) 596, ISSN 2380-6591
Publisher: JAMA Network
DOI: 10.1001/jamacardio.2019.1189

The Long Quest for the Holy Grail in Transcatheter Aortic Bioprosthesis: Durability and Long-Term Performance

Author(s): Patrizio Lancellotti, Christophe Martinez, Marc Radermecker
Published in: Journal of the American College of Cardiology, 2019, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2018.11.043

Global and regional myocardial function and outcomes after transcatheter aortic valve implantation for aortic stenosis and preserved ejection fraction

Author(s): Vlatka Reskovic Luksic, Adriana Postolache, Christophe Martinez, Raluca Dulgheru, Federica Ilardi, Julien Tridetti, Mai-Linh Nguyen, Caroline Piette, Marijan Pasalic, Josko Bulum, Jadranka Separovic Hanzevacki, Patrizio Lancellotti
Published in: Journal of Cardiovascular Medicine, Issue 21/3, 2020, Page(s) 238-245, ISSN 1558-2027
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.2459/jcm.0000000000000918

Synthesis of ticagrelor analogues belonging to 1,2,3-triazolo[4,5-d]pyrimidines and study of their antiplatelet and antibacterial activity

Author(s): Eric Goffin, Nicolas Jacques, Lucia Musumeci, Alain Nchimi, Cécile Oury, Patrizio Lancellotti, Bernard Pirotte
Published in: European Journal of Medicinal Chemistry, 2020, ISSN 0223-5234
Publisher: Elsevier BV
DOI: 10.1016/j.ejmech.2020.112767

Intervention In Severe Aortic Stenosis

Author(s): Mani A. Vannan, Julien Tridetti, Patrizio Lancellotti
Published in: Journal of the American College of Cardiology, Issue 75/19, 2020, Page(s) 2459-2462, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2020.04.007

Prosthetic Aortic Valves: Challenges and Solutions

Author(s): Lucia Musumeci, Nicolas Jacques, Alexandre Hego, Alain Nchimi, Patrizio Lancellotti, Cécile Oury
Published in: Frontiers in Cardiovascular Medicine, Issue 5, 2018, ISSN 2297-055X
Publisher: Frontiers
DOI: 10.3389/fcvm.2018.00046

Predicting Disease Progression and Mortality in Aortic Stenosis: A Systematic Review of Imaging Biomarkers and Meta-Analysis

Author(s): Alain Nchimi, John E. Dibato, Laurent Davin, Laurent Schoysman, Cécile Oury, Patrizio Lancellotti
Published in: Frontiers in Cardiovascular Medicine, Issue 5, 2018, ISSN 2297-055X
Publisher: Frontiers
DOI: 10.3389/fcvm.2018.00112

Outcomes of Patients With Asymptomatic Aortic Stenosis Followed Up in Heart Valve Clinics

Author(s): Patrizio Lancellotti, Julien Magne, Raluca Dulgheru, Marie-Annick Clavel, Erwan Donal, Mani A. Vannan, John Chambers, Raphael Rosenhek, Gilbert Habib, Guy Lloyd, Stefano Nistri, Madalina Garbi, Stella Marchetta, Khalil Fattouch, Augustin Coisne, David Montaigne, Thomas Modine, Laurent Davin, Olivier Gach, Marc Radermecker, Shizhen Liu, Linda Gillam, Andrea Rossi, Elena Galli, Federica Ilardi, Lion
Published in: JAMA Cardiology, 2018, ISSN 2380-6583
Publisher: JAMA Network
DOI: 10.1001/jamacardio.2018.3152

Can Blood Biomarkers Help Predicting Outcome in Transcatheter Aortic Valve Implantation?

Author(s): Cécile Oury, Alain Nchimi, Patrizio Lancellotti, Jutta Bergler-Klein
Published in: Frontiers in Cardiovascular Medicine, Issue 5, 2018, ISSN 2297-055X
Publisher: Frontiers
DOI: 10.3389/fcvm.2018.00031

Heart Valve Specialist Core Syllabus of the ESC Council on Valvular Heart Disease

Author(s): Madalina Garbi, Patrizio Lancellotti
Published in: European Heart Journal, Issue 41/43, 2020, Page(s) 4156-4156, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehaa778

Tackling prosthetic heart valve-related deterioration: Liège translational cardiovascular research programme

Author(s): Patrizio Lancellotti, Nicolas Jacques, Cécile Oury
Published in: Eurointervention, 2020, ISSN 1774-024X
Publisher: Europa Ed
DOI: 10.4244/eijv15i17a272

Early Surgery in Infective Endocarditis

Author(s): Michael J. Mack, Patrizio Lancellotti
Published in: Journal of the American College of Cardiology, Issue 76/1, 2020, Page(s) 41-42, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2020.05.049

Heart Valve Clinics, Centers, and Networks

Author(s): John B. Chambers, Patrizio Lancellotti
Published in: Cardiology Clinics, Issue 38/1, 2020, Page(s) 65-74, ISSN 0733-8651
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.ccl.2019.09.006

Case report: aortic bioprosthesis marantic endocarditis

Author(s): Clara Douin, Stella Marchetta, Raluca Dulgheru, Pierre-Julien Bruyères, Marie Moonen, Patrizio Lancellotti
Published in: Acta Cardiologica, 2020, Page(s) 1-2, ISSN 0001-5385
Publisher: Association Royale des Societes Scientifiques Medicales Belges/Koninklijke Vereniging van de Belgische Medische Wetenschappelijke Genootschappen
DOI: 10.1080/00015385.2020.1813995

Conference proceedings (1)

A Novel Antithrombotic Coating for Blood-contacting Medical Devices

Author(s): L. Musumeci, A. Aqil, N. Jacques, C. Jérôme, A. Nchimi, P. Lancellotti, C. Oury
Published in: 2019
Publisher: ISTH Academy

Intellectual Property Rights

Patent (8)

NANORESERVOIRS

Application/Publication number: 20 17084728
Date: 2017-12-28

PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTIONS

Application/Publication number: 20 19053711
Date: 2019-02-14

NEW PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF GRAM-NEGATIVE BACTERIAL INFECTION, CONTAMINATION AND FOULING

Application/Publication number: 20 20060819
Date: 2020-04-17

NEW USE OF TRIAZOLO(4,5-D)PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTION

Application/Publication number: EP 16188201
Date: 2016-09-09

NEW USE OF TRIAZOLO(4,5-D)PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTION

Application/Publication number: EP 16188201
Date: 2016-09-09

TRIAZOLO(4,5-D)PYRIMIDINE DERIVATIVES FOR USE IN THE PREVENTION AND TREATMENT OF BACTERIAL INFECTION

Application/Publication number: 16 188201
Date: 2016-09-09

NEW USE OF TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES

Application/Publication number: 20 20070721
Date: 2020-07-22

NEW USE OF TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES

Application/Publication number: 20 20070721
Date: 2020-07-22