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In-cell NMR monitoring of alpha-Synuclein aggregation in neuronal cells


Quantitative mass imaging of single biological macromolecules

Author(s): Gavin Young, Nikolas Hundt, Daniel Cole, Adam Fineberg, Joanna Andrecka, Andrew Tyler, Anna Olerinyova, Ayla Ansari, Erik G. Marklund, Miranda P. Collier, Shane A. Chandler, Olga Tkachenko, Joel Allen, Max Crispin, Neil Billington, Yasuharu Takagi, James R. Sellers, Cédric Eichmann, Philipp Selenko, Lukas Frey, Roland Riek, Martin R. Galpin, Weston B. Struwe, Justin L. P. Benesch, Philipp Kukura
Published in: Science, 360/6387, 2018, Page(s) 423-427, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aar5839

Structural Biology outside the box — inside the cell

Author(s): Jürgen M Plitzko, Benjamin Schuler, Philipp Selenko
Published in: Current Opinion in Structural Biology, 46, 2017, Page(s) 110-121, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/

Structural disorder of monomeric α-synuclein persists in mammalian cells

Author(s): Francois-Xavier Theillet, Andres Binolfi, Beata Bekei, Andrea Martorana, Honor May Rose, Marchel Stuiver, Silvia Verzini, Dorothea Lorenz, Marleen van Rossum, Daniella Goldfarb, Philipp Selenko
Published in: Nature, 530/7588, 2016, Page(s) 45-50, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature16531

Opposing effects of Elk-1 multisite phosphorylation shape its response to ERK activation

Author(s): A. Mylona, F.-X. Theillet, C. Foster, T. M. Cheng, F. Miralles, P. A. Bates, P. Selenko, R. Treisman
Published in: Science, 354/6309, 2016, Page(s) 233-237, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aad1872

Intracellular repair of oxidation-damaged α-synuclein fails to target C-terminal modification sites

Author(s): Andres Binolfi, Antonio Limatola, Silvia Verzini, Jonas Kosten, Francois-Xavier Theillet, Honor May Rose, Beata Bekei, Marchel Stuiver, Marleen van Rossum, Philipp Selenko
Published in: Nature Communications, 7, 2016, Page(s) 10251, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/ncomms10251

In-Cell Protein Structures from 2D NMR Experiments

Author(s): Thomas Müntener, Daniel Häussinger, Philipp Selenko, Francois-Xavier Theillet
Published in: The Journal of Physical Chemistry Letters, 7/14, 2016, Page(s) 2821-2825, ISSN 1948-7185
Publisher: American Chemical Society
DOI: 10.1021/acs.jpclett.6b01074