How neuronal activity patterns drive behavior: novel all-optical control and monitoring of brain neuronal networks with high spatiotemporal resolution

Project Information

NEURO-PATTERNS

Grant agreement ID: 647725

DOI 10.3030/647725

Project closed

EC signature date 23 July 2015

Start date 1 October 2015

End date 31 March 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 974 000,00

EU contribution € 1 974 000,00

Coordinated by

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy

Publications

Peer reviewed articles (13)

Optogenetic strategies for high-efficiency all-optical interrogation using blue light-sensitive opsins

Author(s): Angelo Forli, Matteo Pisoni, Yoav Printz, Ofer Yizhar, Tommaso Fellin
Published in: eLife, Issue 10, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.63359

Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes

Author(s): Letizia Mariotti, Gabriele Losi, Annamaria Lia, Marcello Melone, Angela Chiavegato, Marta Gómez-Gonzalo, Michele Sessolo, Serena Bovetti, Angelo Forli, Micaela Zonta, Linda Maria Requie, Iacopo Marcon, Arianna Pugliese, Cécile Viollet, Bernhard Bettler, Tommaso Fellin, Fiorenzo Conti, Giorgio Carmignoto
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-02642-6

An inhibitory gate for state transition in cortex

Author(s): Stefano Zucca, Giulia D’Urso, Valentina Pasquale, Dania Vecchia, Giuseppe Pica, Serena Bovetti, Claudio Moretti, Stefano Varani, Manuel Molano-Mazón, Michela Chiappalone, Stefano Panzeri, Tommaso Fellin
Published in: eLife, Issue 6, 2017, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.26177

Two-Photon Bidirectional Control and Imaging of Neuronal Excitability with High Spatial Resolution In Vivo

Author(s): Angelo Forli, Dania Vecchia, Noemi Binini, Francesca Succol, Serena Bovetti, Claudio Moretti, Francesco Nespoli, Mathias Mahn, Christopher A. Baker, McLean M. Bolton, Ofer Yizhar, Tommaso Fellin
Published in: Cell Reports, Issue 22/11, 2018, Page(s) 3087-3098, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2018.02.063

Scanless functional imaging of hippocampal networks using patterned two-photon illumination through GRIN lenses

Author(s): Claudio Moretti, Andrea Antonini, Serena Bovetti, Carlo Liberale, Tommaso Fellin
Published in: Biomedical Optics Express, Issue 7/10, 2016, Page(s) 3958, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.7.003958

Unaltered Network Activity and Interneuronal Firing During Spontaneous Cortical Dynamics In Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy.

Author(s): De Stasi AM, Farisello P, Marcon I, Cavallari S, Forli A, Vecchia D, Losi G, Mantegazza M, Panzeri S, Carmignoto G, Bacci A, Fellin T
Published in: Cerebral Cortex, Issue 26/4, 2016, Page(s) 1778-1794, ISSN 1047-3211
Publisher: Oxford University Press
DOI: 10.1093/cercor/bhw002

Simultaneous high-speed imaging and optogenetic inhibition in the intact mouse brain

Author(s): Serena Bovetti, Claudio Moretti, Stefano Zucca, Marco Dal Maschio, Paolo Bonifazi, Tommaso Fellin
Published in: Scientific Reports, Issue 7, 2017, Page(s) 40041, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/srep40041

Cracking the Neural Code for Sensory Perception by Combining Statistics, Intervention, and Behavior

Author(s): Panzeri S, Harvey CD, Piasini E, Latham PE, Fellin T
Published in: Neuron, 2017, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2016.12.036

Temporal Sharpening of Sensory Responses by Layer V in the Mouse Primary Somatosensory Cortex

Author(s): Dania Vecchia, Riccardo Beltramo, Fabio Vallone, Ronan Chéreau, Angelo Forli, Manuel Molano-Mazón, Tanika Bawa, Noemi Binini, Claudio Moretti, Anthony Holtmaat, Stefano Panzeri, Tommaso Fellin
Published in: Current Biology, Issue 30/9, 2020, Page(s) 1589-1599.e10, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2020.02.004

High-Accuracy Detection of Neuronal Ensemble Activity in Two-Photon Functional Microscopy Using Smart Line Scanning

Author(s): Marco Brondi, Monica Moroni, Dania Vecchia, Manuel Molano-Mazón, Stefano Panzeri, Tommaso Fellin
Published in: Cell Reports, Issue 30/8, 2020, Page(s) 2567-2580.e6, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.01.105

Thalamic Drive of Cortical Parvalbumin-Positive Interneurons during Down States in Anesthetized Mice

Author(s): Stefano Zucca, Valentina Pasquale, Pedro Lagomarsino de Leon Roig, Stefano Panzeri, Tommaso Fellin
Published in: Current Biology, Issue 29/9, 2019, Page(s) 1481-1490.e6, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2019.04.007

The Spectrum of Asynchronous Dynamics in Spiking Networks as a Model for the Diversity of Non-rhythmic Waking States in the Neocortex

Author(s): Yann Zerlaut, Stefano Zucca, Stefano Panzeri, Tommaso Fellin
Published in: Cell Reports, Issue 27/4, 2019, Page(s) 1119-1132.e7, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.03.102

Extended field-of-view ultrathin microendoscopes for high-resolution two-photon imaging with minimal invasiveness

Author(s): Andrea Antonini, Andrea Sattin, Monica Moroni, Serena Bovetti, Claudio Moretti, Francesca Succol, Angelo Forli, Dania Vecchia, Vijayakumar P Rajamanickam, Andrea Bertoncini, Stefano Panzeri, Carlo Liberale, Tommaso Fellin
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.58882