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Description of information transfer across macromolecules by concerted conformational changes

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Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer

Author(s): Laura Cato, Antje Neeb, Adam Sharp, Victor Buzón, Scott B Ficarro, Linxiao Yang, Claudia Muhle-Goll, Nane C Kuznik, Ruth Riisnaes, Daniel Nava Rodrigues, Olivier Armant, Victor Gourain, Guillaume Adelmant, Emmanuel A Ntim, Thomas Westerling, David Dolling, Pasquale Rescigno, Ines Figueiredo, Friedrich Fauser, Jennifer Wu, Jaice T Rottenberg, Liubov Shatkina, Claudia Ester, Burkhard Luy, Holger Pu
Published in: eLife, 6, 2017, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.27159

Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators.

Author(s): De Mol E, Szulc E, Di Sanza C, Martínez-Cristóbal P, Bertoncini CW, Fenwick RB, Frigolé-Vivas M, Masín M, Hunter I, Buzón V, Brun-Heath I, García J, De Fabritiis G, Estébanez-Perpiñá E, McEwan IJ, Nebreda ÁR, Salvatella X.
Published in: Structure, 2018, ISSN 0969-2126
Publisher: Cell press

Sequence Context Influences the Structure and Aggregation Behavior of a PolyQ Tract

Author(s): Bahareh Eftekharzadeh, Alessandro Piai, Giulio Chiesa, Daniele Mungianu, Jesús García, Roberta Pierattelli, Isabella C. Felli, Xavier Salvatella
Published in: Biophysical journal, 2016, Page(s) 2361-2366, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2016.04.022

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

Author(s): Eva De Mol, R. Bryn Fenwick, Christopher T. W. Phang, Victor Buzón, Elzbieta Szulc, Alex de la Fuente, Albert Escobedo, Jesús García, Carlos W. Bertoncini, Eva Estébanez-Perpiñá, Iain J. McEwan, Antoni Riera, and Xavier Salvatella
Published in: ACS Chemical Biology, 2016, Page(s) 2499-2505, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.6b00182