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A platform for the generation of human gametes in vitro

Objective

According to the World Health Organization, infertility is a medical condition that affects up to 14% of couples under reproductive age. The increase in infertility has led to the exponential rise in the use of assisted reproduction as a route for conceiving a baby, currently representing 1.5% of children born in Europe. Although multiple factors may contribute to infertility, the limited availability of human gametes for its study restricts the capacity of researchers in establishing the causes of this decline. To address this limitation, a talented Fellow with background in physiology of reproduction will join a leading laboratory in developmental biology to conduct multidisciplinary research aimed at developing a platform for the generation of human gametes in the laboratory. A combination of state-of-the-art tools in genomics and cell biology will be used to gain new understanding of how gamete precursors form in vivo, and this knowledge will be used to develop culture systems to generate gametes in vitro. These approaches will equip the Fellow with comprehensive new skills essential for fulfilling these objectives. The transfer of knowledge builds on the host’s expertise in animal biotechnology, the provision of interdisciplinary training in human stem cell differentiation by collaborators, and on the Fellow’s knowledge of reproductive biology. The output of the project will address key societal challenges for the EU in the areas of Health, demographic change and well-being and will contribute to the expansion of the network of experts in biotechnology.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2014

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Coordinator

THE UNIVERSITY OF NOTTINGHAM
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 183 454,80
Address
University Park
NG7 2RD Nottingham
United Kingdom

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Region
East Midlands (England) Derbyshire and Nottinghamshire Nottingham
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 183 454,80
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