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Genomic and epigenomic signatures of climate-mediated selection in cattle

Objective

Official assessments of climate change impacts in Europe predict substantial economic losses due to the progressive upward trend in average temperatures over the next century, and the decrease in annual accumulated rainfall. Global warming will lead to a decreased forage production and quality, and an increased disease risk, which will significantly change conditions for livestock production. Therefore, increasing climate resilience and enhancing sustainable production for animals in harsh environments are important goals for the livestock industry. Fortunately, a natural experiment already exists where a rapid adaptation to extreme climatic conditions was imposed on a limited number of livestock, Columbus’ arrival in the Americas, which therefore provides a model system to study adaptive selection. Given the accumulating evidence that epigenetic processes may increase the evolutionary potential of organisms to respond to stress and other challenges, the aim of this project is to compare the genomes and methylomes of two tropical Creole bovine breeds, their main Spanish ancestors, and one taurine breed from Africa, to understand rapid adaptation to extreme climatic conditions and identifying biomarkers of resilience. The anticipated outcomes from this project will help in designing management systems to improve productivity, thermal and stress tolerance, and disease resistance in cattle.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2014

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Coordinator

CARDIFF UNIVERSITY
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 183 454,80
Address
RESEARCH SERVICES C/O MAIN BUILDING
CF10 3AT CARDIFF
United Kingdom

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Region
Wales East Wales Cardiff and Vale of Glamorgan
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 183 454,80
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