Structural and functional studies of LARP4, a new RNA binding protein involved in mRNA stabilisation and cell migration

Project Information

LARP4MOT

Grant agreement ID: 655341

DOI 10.3030/655341

Project closed

EC signature date 17 March 2015

Start date 1 September 2016

End date 31 August 2018

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 183 454,80

EU contribution € 183 454,80

Coordinated by

KING'S COLLEGE LONDON
United Kingdom

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Publications

Peer reviewed articles (3)

The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives

Author(s): Richard J. Maraia, Sandy Mattijssen, Isabel Cruz-Gallardo, Maria R. Conte
Published in: Wiley Interdisciplinary Reviews: RNA, Issue 8/6, 2017, Page(s) e1430, ISSN 1757-7004
Publisher: John Wiley and Sons Inc.
DOI: 10.1002/wrna.1430

Resonance assignment of human LARP4A La module

Author(s): Isabel Cruz-Gallardo, Luigi Martino, Roberta Trotta, Stefano De Tito, Geoff Kelly, R. Andrew Atkinson, Antonio Randazzo, Maria R. Conte
Published in: Biomolecular NMR Assignments, 2019, ISSN 1874-2718
Publisher: Springer Verlag
DOI: 10.1007/s12104-019-09871-4

LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA

Author(s): Isabel Cruz-Gallardo, Luigi Martino, Geoff Kelly, R Andrew Atkinson, Roberta Trotta, Stefano De Tito, Pierre Coleman, Zainab Ahdash, Yifei Gu, Tam T T Bui, Maria R Conte
Published in: Nucleic Acids Research, Issue 47/8, 2019, Page(s) 4272-4291, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkz144