Periodic Reporting for period 1 - ChloroQuality (Dissecting chloroplast protein quality control specificity for rational plant reprogramming)
Reporting period: 2016-01-01 to 2017-12-31
While the composition and structure of chloroplastic high molecular protein complexes such as photosystems or ribosomes is well characterized, less information is available about their regulation, specially under stress situations. Similarly to other compartments, chaperones and proteases are required to monitor protein homeostasis in the chloroplast, assisting the folding, assembly and degradation of proteins during their lifetime. Although several types of chaperones are known to assist in the correct functioning of the chloroplast, the molecular basis behind these requirements remain unknown. Thus, it is necessary to increase our understanding of how the levels and the activity of chloroplastic proteins are regulated. ChloroQuality address this challenge by studying the DNAJ protein family of chaperones in the plant model Arabidopsis thaliana.