Periodic Reporting for period 1 - EvoNovo (Genetic architecture of an evolutionary novelty: the development of the male-specific turban-shaped eyes of Cloeon dipterum)
Reporting period: 2016-01-01 to 2017-12-31
To investigate the appearance of the turbanate eye in C. dipterum, we combined a number of experimental approaches, including non-invasive imaging, gene expression analyses, genomics, transcriptomics, and epigenomics to knit the gene regulatory network responsible for the development of the turbanate eye. EvoNovo described the formation of this new organ in males and the regulatory networks that have evolved to originate this structure in the males of this species.
In addition, the establishment of C. dipterum as a model serves to other researchers as a foundation for further investigations in an organism placed in a key position in the phylogeny of insects.
These findings have been presented in several national and international scientific meetings, and talks to the general public and they will be publicly available after the publication of the results in high impact factor journals as open access manuscripts
To gain these new insights we have generated during this project multiple resources, tools and datasets that will be of great help to the scientific community. This includes the establishment of this mayfly as a model system, functional tools and the generation of gene expression and genomic datasets that will have a broad impact to other researchers in future comparative studies.
Furthermore, the dissemination efforts carried out during the project have increased the current awareness of the importance of evolutionary studies and basic research among the general public.
In conclusion, EvoNovo will boost the formulation of new hypotheses, ideas and new research lines in the evodevo, genomics and developmental biology fields.