Development of Palladium-Labile Prodrugs for Bioorthogonally-Activated Chemotherapy

Project Information

ChemoBOOM

Grant agreement ID: 658833

DOI 10.3030/658833

Project closed

EC signature date 25 March 2015

Start date 1 February 2016

End date 31 January 2018

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 183 454,80

EU contribution € 183 454,80

Coordinated by

THE UNIVERSITY OF EDINBURGH
United Kingdom

Publications

Peer reviewed articles (3)

Gold-Triggered Uncaging Chemistry in Living Systems

Author(s): Ana M. Pérez-López, Belén Rubio-Ruiz, Víctor Sebastián, Lloyd Hamilton, Catherine Adam, Thomas L. Bray, Silvia Irusta, Paul M. Brennan, Guy C. Lloyd-Jones, Dirk Sieger, Jesús Santamaría, Asier Unciti-Broceta
Published in: Angewandte Chemie International Edition, Issue 56/41, 2017, Page(s) 12548-12552, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201705609

High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy

Author(s): Belén Rubio-Ruiz, Ana M. Pérez-López, Thomas L. Bray, Martin Lee, Alan Serrels, Martín Prieto, Manuel Arruebo, Neil O. Carragher, Víctor Sebastián, Asier Unciti-Broceta
Published in: ACS Applied Materials & Interfaces, Issue 10/4, 2018, Page(s) 3341-3348, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.7b17282

Efficient Palladium-Triggered Release of Vorinostat from a Bioorthogonal Precursor

Author(s): Belén Rubio-Ruiz, Jason T. Weiss, Asier Unciti-Broceta
Published in: Journal of Medicinal Chemistry, Issue 59/21, 2016, Page(s) 9974-9980, ISSN 0022-2623
Publisher: American Chemical Society
DOI: 10.1021/acs.jmedchem.6b01426