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Multi-functional Computational Microscopy for Quantitative Cell Tracking

Objective

Quantitative assessment of cellular phenotypes can result from various processes such as genetic manipulation, gene silencing, drug application or environmental changes. In many biological processes evident development of phenotypes often requires a long-term study of the sample, which can capture events at high-resolution and high frame rates. The essential working tool for this kind of studies is the optical microscope, which is essentially limited by a small field of view of the sample in two-dimensional (2D) environment, unsuitable for the quantitative assessment of cells in a more natural environment, in which they develop and evolve within complex communities. For this task, I purpose a novel platform based on a holographic on-chip microscopy which represents a new generation of computational microscopes, by integrating transformative technologies, which will ultimately enable five-dimensional, photodamage optimized at diffraction limited resolution, quantitative cell tracking. We believe that these functionalities and the platform's cost effectiveness will enable next generation high-throughput scientific research on the influence of drugs, genome modification and environmental changes, developing new models for cell locomotion, such as viral plague growth assays performed in hospitals and clinics, detection of parasites and bacteria in food/water and for education purposes, including in developing countries.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-GF - Global Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2014

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Coordinator

BAR ILAN UNIVERSITY
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 263 385,00
Address
BAR ILAN UNIVERSITY CAMPUS
52900 Ramat Gan
Israel

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Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 263 385,00

Partners (1)

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