Objective
In the follow-up project mathematical tools and software that have been developed in the Marie Curie Individual Fellowship FIGH-CT-2002-50513 will be used and extended for continued research in the field of risk estimation of low doses of ionising radiation via mechanistic cancer models. The intention is to continue to collaborate with the partners at RIVM and to also extend ongoing projects with collaborators in the US (Purdue University) and Canada (Chalk River Laboratories).
Recently published data (Mitcheletal., Radiat Res 159(3): 320-327, 2003) which show that low doses of gamma-radiation delivered at low dose-rates increase tumour latency of spontaneous lymphomas and spinal osteosarcomas in mice will be used to test the model. Biological mechanisms other than those already implemented in the mechanistic cancer model will be incorporated. In addition it is planned to incorporate detrimental and protective bystander effects into the cancer model. Possible technical extensions of the software that was produced in the ongoing Marie Curie Individual Fellowship are Monte Carlo simulations using the Crystal Ball Pro software.
The aim is to include those biological mechanisms into the cancer model that are most relevant at low doses of ionising radiation. Mode l simulations are then performed to see which mechanisms dominate in the low dose region and to predict the shape of the dose-response relationship at low doses of ionising radiation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences software
- natural sciences biological sciences genetics DNA
- medical and health sciences clinical medicine oncology lung cancer
- natural sciences biological sciences genetics chromosomes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
SALZBURG
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.