Predicting Cardiotoxicity Induced by Kinase Inhibitors: From Systems Biology to Systems Pharmacology

Project Information

CARDIOTOX

Grant agreement ID: 661588

DOI

10.3030/661588

Project closed

EC signature date 16 March 2015

Start date 6 December 2015

End date 5 December 2018

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 242 929,80

EU contribution

€ 242 929,80

Coordinated by

UNIVERSITEIT LEIDEN
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (2)

Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics

Author(s): Jaehee V. Shim, Bryan Chun, Johan G. C. van Hasselt, Marc R. Birtwistle, Jeffrey J. Saucerman, Eric A. Sobie
Published in: Frontiers in Physiology, Issue 8, 2017, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2017.00651

Systems pharmacology-based identification of pharmacogenomic determinants of adverse drug reactions using human iPSC-derived cell lines

Author(s): J.G. Coen van Hassselt, Ravi Iyengar
Published in: Current Opinion in Systems Biology, Issue 4, 2017, Page(s) 9-15, ISSN 2452-3100
Publisher: Elsevier
DOI: 10.1016/j.coisb.2017.05.006