Liquid Biopsy blood test in lung cancer diagnosis and monitoring: a next generation noninvasive tumor tracker device

Objective

The ultimate objective of the Celletest project is to develop a next generation medical device for non-invasive diagnosis and prognosis of metastatic lung cancer, so we can validate the . To achieve this ambitious objective, we will exploit the potential of our proprietary technology for isolation of circulating tumor cells from the bloodstream, so we can validate the clinical utility of CTCs, which have been already identified as biomarkers for the liquid-biopsy of metastatic lung cancers.
What is a Liquid Biopsy? Liquid biopsy is an emerging and disruptive technology in cancer diagnosis, prognosis and monitoring of evolution of cancer patients under anticancer therapies. This novel technology can be understood as the next generation non-invasive alternative to the current gold standard in cancer diagnosis, tissue biopsy. Tissue biopsy implies an interventional/surgical procedure to sample cells or tissue at the tumor site. The biopsied tissue is examined and analyzed (molecular characterization for the determination of the molecular biomarkers of cancer cells) in order to characterize the cancer cells according to their morphological and biochemical properties. This allows determining the tumor typology and prescribing the most optimal anticancer therapy. Liquid biopsy holds promise as a non-invasive method capable to obtain the same clinically relevant information with just a simple blood extraction.

Field of science

• /engineering and technology/medical engineering/medical laboratory technology/laboratory samples analysis
• /medical and health sciences/clinical medicine/surgery/surgical procedure
• /social sciences/sociology/gender studies/gender equality
• /natural sciences/biological sciences/cell biology
• /medical and health sciences/clinical medicine/cancer
• /social sciences/economics and business/business and management/commerce

Programme(s)

• H2020-EU.3.1.3. - Treating and managing disease

Topic(s)

• PHC-12-2014-1 - Clinical research for the validation of biomarkers and/or diagnostic medical devices

Call for proposal

H2020-SMEINST-1-2014
See other projects for this call

Funding Scheme

SME-1 - SME instrument phase 1

Coordinator

STEM SEL SRL

Address

Viale Giuseppe Fanin 48
40127 Bologna
Italy

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

EU contribution

€ 50 000