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Development of a Chimpanzee Adenovirus Type 3 Ebolavirus Zaire Vaccine

Deliverables

Clinical study report

Clinical study report

Registration number of clinical trial in ClinicalTrials.gov and Swiss National Clinical Trials Portal

Registration number of clinical trial in ClinicalTrials.gov and Swiss National Clinical Trials Portal

Clearances from ethic committees and regulatory authorities

Clearances from ethic committees and regulatory authorities

Report on status of posting results in the study registry

Report on status of posting results in the study registry

Registration No. of Senegal clinical study in a WHO or ICMJE approved registry

Registration No. of Senegal clinical study in a WHO or ICMJE approved registry

Web based platform live

the web-based management platform will be built and operational within the first 6 months of the project (GSK). Then, the content will be regularly updated.

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Publications

Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study

Author(s): Olga De Santis, Régine Audran, Emilie Pothin, Loane Warpelin-Decrausaz, Laure Vallotton, Grégoire Wuerzner, Camille Cochet, Daniel Estoppey, Viviane Steiner-Monard, Sophie Lonchampt, Anne-Christine Thierry, Carole Mayor, Robert T Bailer, Olivier Tshiani Mbaya, Yan Zhou, Aurélie Ploquin, Nancy J Sullivan, Barney S Graham, François Roman, Iris De Ryck, W Ripley Ballou, Marie Paule Kieny, Vasee M
Published in: The Lancet Infectious Diseases, Issue 16/3, 2016, Page(s) 311-320, ISSN 1473-3099
DOI: 10.1016/S1473-3099(15)00486-7

A review of Phase I trials of Ebola virus vaccines: what can we learn from the race to develop novel vaccines?

Author(s): Teresa Lambe, Georgina Bowyer, Katie J Ewer
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 372/1721, 2017, Page(s) 20160295, ISSN 0962-8436
DOI: 10.1098/rstb.2016.0295