Control of the Ebola Oubreak by both innovative Ultrasensitive Detection of EBOV and therapy

Deliverables

Documents, reports (3)

Ebola virus diversity assessed by sequencing

The report will provide an overview of Ebola virus diversity as assessed by sequencing necessary to optimize the diagnostic, treatment and vaccine approaches.

Whole infectious profiles

The report will provide an overview of the diversity of infectious profiles from available samples.

Ethical regulations, security and safety set up for diagnostic and follow-up of patients of the phase 1 (without treatment)

Ethical regulations set up to work with the present project for diagnostic and treatment

Websites, patent fillings, videos etc. (1)

Creation of the specific website of the project

Creation of the specific website of the project.

Publications

Conference proceedings (11)

Metagenomic analyses and genomic fingerprint of co-infections of the EBOLA viral disease

Author(s): W. Valdivia-, D. Sheoran, G. Dubois, S. Tigrett, F. Veas
Published in: 2015
Publisher: Tofo conference on Filovirus, Ebola and Other Filoviruses

Development of a specific polyclonal immunoglobulin against Ebola

Author(s): C. Herbreteau & IF Ebola
Published in: 2015
Publisher: First World Congress on Targeting Ebola

Lessons Learned from the Development of an Ebola Immunotherapy

Author(s): R Metrop, JF Saluzzo, F Veas, C. Herbreteau
Published in: 2017
Publisher: IV International Conference on Mitigation Strategies for Emerging Infectious diseases

Specific polyclonal F(ab’)2immunoglobulin fragments; in vitro characterization and in vivo effectiveness in post-exposure treatment against Zaire Ebola virus in mice

Author(s): M. Denizot, T. Racine, D. Pannetier, A. Pasquier, H. Raoul, JF Saluzzo, G. Kobinger, F. Veas, C. Herbreteau
Published in: 2017
Publisher: The II International Conference CBRNE - Research & Innovation

Atypical immune response of EVD Long-term survivors

Author(s): Y. Eskira A Sobarzo, F Veas L Lobel
Published in: 2017
Publisher: VIII International Conference on Emerging Zoonoses and transboundary Infectious Diseases

The preparedness IF-EBOLA toolbox for rapid and efficient mitigation of upcoming outbreaks. A platform model for emerging diseases

Author(s): F.Veas
Published in: 2016
Publisher: International Conference on Mitigation Strategies for Emerging Infectious diseases

Efficiency of innovative preparedness IF-EBOLA technologies: Ultrasensitive diagnostics, horse anti-Ebola virus polyclonal Fabs & metagenomic analyses of Ebola variants and co-infections

Author(s): F.Veas
Published in: 2017
Publisher: IV International Conference on Mitigation Strategies for Emerging Infectious diseases

Ebola virus Genomic and Metagenomic signature Analyses of the 2014-15 West African Outbreak

Author(s): W. Valdivia, D. Sheoran, & F. Veas
Published in: 7th Filovirus Conference, 2015
Publisher: 7th Filovirus Conference

Multi-technological platforms to solve unmet needs for rapid and efficient management of emerging diseases

Author(s): F.Veas
Published in: 2015
Publisher: XIX International Congress for Tropical Diseases

A Universal virus capture method leading to a rapid and ultrasensitive detection of pathogens for early & late post-exposure countermeasures

Author(s): S Tigrett, L Lobel, F Veas
Published in: 2017
Publisher: VIII International Conference on Emerging Zoonoses and transboundary Infectious diseases

RIGEL as a Powerful Computational Architecture for Genomic & Metagenomic Signature Discrimination: Analysis of the 2014-15 West African EBOLA Outbreak”

Author(s): W. Valdivia, D. Sheoran & F. Veas
Published in: Gordon Research Conferences, on Biodefense and Bioterrorism meeting, 2015, Page(s) March 8-13, 2015
Publisher: Gordon Research Conference

Other (1)

Resveratrol-Linoleate protects from exacerbated endothelial permeability via a drastic inhibition of the MMP-9 activity

Author(s): A Shamseddin, C Crauste, E Durand, P Villeneuve, G Dubois, T Pavlickova, Th Durand, J. Vercauteren, and F Veas
Published in: 2018
Publisher: BioScience Reports 2018

Peer reviewed articles (1)

Resveratrol formulated with a natural deep eutectic solvent inhibits active matrix metalloprotease-9 in hormetic conditions

Author(s): Aly Shamseddin, Céline Crauste, Erwann Durand, Pierre Villeneuve, Gregor Dubois, Thierry Durand, Joseph Vercauteren, Francisco Veas
Published in: European Journal of Lipid Science and Technology, 119/11, 2017, Page(s) 1700171, ISSN 1438-7697
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/ejlt.201700171