Data-driven models for Progression Of Neurological Disease

Providing fundamental new knowledge on dementia subtypes.

Dissemination of our framework.

Communication (internal and external) of results, and for online meetings.

Getting a reference point (normal ageing) for sporadic neurological diseases.

Multimodal models of changes in prion disease.

Developing disease understanding.

Dissemination of our unified modelling framework.

A new formulation of these models.

How such models fit into the framework.

Advancing models for features and robustness.

Answering key questions.

Update to the event-based model of disease progression.

Multimodal models of changes in MS.

This will have primary Impact within the research community, but will be developed with clinical usage in mind.

A new formulation of these models.

Author(s): L. Gui, S. Loukas, F. Lazeyras, P.S. Hüppi, D.E. Meskaldji, C. Borradori Tolsa
Published in: NeuroImage, Issue 185, 2019, Page(s) 728-741, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2018.06.034

Author(s): W. Huizinga, D.H.J. Poot, M.W. Vernooij, G.V. Roshchupkin, E.E. Bron, M.A. Ikram, D. Rueckert, W.J. Niessen, S. Klein
Published in: NeuroImage, Issue 169, 2018, Page(s) 11-22, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2017.10.040

Author(s): Elisabeth J. Vinke, Marius de Groot, Vikram Venkatraghavan, Stefan Klein, Wiro J. Niessen, M. Arfan Ikram, Meike W. Vernooij
Published in: Neurobiology of Aging, Issue 71, 2018, Page(s) 32-40, ISSN 0197-4580
DOI: 10.1016/j.neurobiolaging.2018.07.001

Author(s): Igor Koval, Jean-Baptiste Schiratti, Alexandre Routier, Michael Bacci, Olivier Colliot, Stéphanie Allassonnière, Stanley Durrleman
Published in: Frontiers in Neurology, Issue 9, 2018, ISSN 1664-2295
DOI: 10.3389/fneur.2018.00235

Author(s): Arman Eshaghi, Razvan V Marinescu, Alexandra L Young, Nicholas C Firth, Ferran Prados, M Jorge Cardoso, Carmen Tur, Floriana De Angelis, Niamh Cawley, Wallace J Brownlee, Nicola De Stefano, M Laura Stromillo, Marco Battaglini, Serena Ruggieri, Claudio Gasperini, Massimo Filippi, Maria A Rocca, Alex Rovira, Jaume Sastre-Garriga, Jeroen J G Geurts, Hugo Vrenken, Viktor Wottschel, Cyra E Leurs, Berna
Published in: Brain, Issue 141/6, 2018, Page(s) 1665-1677, ISSN 0006-8950
DOI: 10.1093/brain/awy088

Author(s): Anne Bertrand, Junhao Wen, Daisy Rinaldi, Marion Houot, Sabrina Sayah, Agnès Camuzat, Clémence Fournier, Sabrina Fontanella, Alexandre Routier, Philippe Couratier, Florence Pasquier, Marie-Odile Habert, Didier Hannequin, Olivier Martinaud, Paola Caroppo, Richard Levy, Bruno Dubois, Alexis Brice, Stanley Durrleman, Olivier Colliot, Isabelle Le Ber
Published in: JAMA Neurology, Issue 75/2, 2018, Page(s) 236, ISSN 2168-6149
DOI: 10.1001/jamaneurol.2017.4266

Author(s): Vikram Venkatraghavan, Esther E. Bron, Wiro J. Niessen, Stefan Klein
Published in: NeuroImage, Issue 186, 2019, Page(s) 518-532, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2018.11.024

Author(s): Neil P Oxtoby, Alexandra L Young, David M Cash, Tammie L S Benzinger, Anne M Fagan, John C Morris, Randall J Bateman, Nick C Fox, Jonathan M Schott, Daniel C Alexander
Published in: Brain, Issue 141/5, 2018, Page(s) 1529-1544, ISSN 0006-8950
DOI: 10.1093/brain/awy050

Author(s): Alexandra L Young, Razvan V Marinescu, Neil P Oxtoby, Martina Bocchetta, Keir Yong, Nicholas C Firth, David M Cash, David L Thomas, Katrina M Dick, Jorge Cardoso, John van Swieten, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B Frisoni, Robert Laforce, Elizabeth Finger, Alexandre de Mendonça, Sandro Sorbi
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
DOI: 10.1038/s41467-018-05892-0

Author(s): Marco Lorenzi, Maurizio Filippone, Giovanni B. Frisoni, Daniel C. Alexander, Sebastien Ourselin
Published in: NeuroImage, Issue 190, 2019, Page(s) 56-68, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2017.08.059

Author(s): Neil P. Oxtoby, Sara Garbarino, Nicholas C. Firth, Jason D. Warren, Jonathan M. Schott, Daniel C. Alexander
Published in: Frontiers in Neurology, Issue 8, 2017, ISSN 1664-2295
DOI: 10.3389/fneur.2017.00580

Author(s): Jorge Samper-González, Ninon Burgos, Simona Bottani, Sabrina Fontanella, Pascal Lu, Arnaud Marcoux, Alexandre Routier, Jérémy Guillon, Michael Bacci, Junhao Wen, Anne Bertrand, Hugo Bertin, Marie-Odile Habert, Stanley Durrleman, Theodoros Evgeniou, Olivier Colliot
Published in: NeuroImage, Issue 183, 2018, Page(s) 504-521, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2018.08.042

Author(s): Răzvan V. Marinescu, Arman Eshaghi, Marco Lorenzi, Alexandra L. Young, Neil P. Oxtoby, Sara Garbarino, Sebastian J. Crutch, Daniel C. Alexander
Published in: NeuroImage, Issue 192, 2019, Page(s) 166-177, ISSN 1053-8119
DOI: 10.1016/j.neuroimage.2019.02.053

Author(s): Meike W. Vernooij, Bas Jasperse, Rebecca Steketee, Marcel Koek, Henri Vrooman, M. Arfan Ikram, Janne Papma, Aad van der Lugt, Marion Smits, Wiro J. Niessen
Published in: NeuroImage: Clinical, Issue 20, 2018, Page(s) 374-379, ISSN 2213-1582
DOI: 10.1016/j.nicl.2018.08.004

Author(s): Lotte G. M. Cremers, Wyke Huizinga, Wiro J. Niessen, Gabriel P. Krestin, Dirk H. J. Poot, M. Arfan Ikram, Jyrki Lötjönen, Stefan Klein, Meike W. Vernooij
Published in: Frontiers in Aging Neuroscience, Issue 11, 2020, ISSN 1663-4365
DOI: 10.3389/fnagi.2019.00379

Author(s): Damiano Archetti, Silvia Ingala, Vikram Venkatraghavan, Viktor Wottschel, Alexandra L. Young, Maura Bellio, Esther E. Bron, Stefan Klein, Frederik Barkhof, Daniel C. Alexander, Neil P. Oxtoby, Giovanni B. Frisoni, Alberto Redolfi
Published in: NeuroImage: Clinical, Issue 24, 2019, Page(s) 101954, ISSN 2213-1582
DOI: 10.1016/j.nicl.2019.101954

Author(s): Sara Garbarino, Marco Lorenzi, Neil P Oxtoby, Elisabeth J Vinke, Razvan V Marinescu, Arman Eshaghi, M Arfan Ikram, Wiro J Niessen, Olga Ciccarelli, Frederik Barkhof, Jonathan M Schott, Meike W Vernooij, Daniel C Alexander
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
DOI: 10.7554/elife.49298

Author(s): Elisabeth J. Vinke, Wyke Huizinga, Martin Bergtholdt, Hieab H. Adams, Rebecca M.E. Steketee, Janne M. Papma, Frank J. de Jong, Wiro J. Niessen, M. Arfan Ikram, Fabian Wenzel, Meike W. Vernooij
Published in: Neurobiology of Aging, Issue 84, 2019, Page(s) 9-16, ISSN 0197-4580
DOI: 10.1016/j.neurobiolaging.2019.07.008

Author(s): Viktor Wottschel, Declan T. Chard, Christian Enzinger, Massimo Filippi, Jette L. Frederiksen, Claudio Gasperini, Antonio Giorgio, Maria A. Rocca, Alex Rovira, Nicola De Stefano, Mar Tintoré, Daniel C. Alexander, Frederik Barkhof, Olga Ciccarelli
Published in: NeuroImage: Clinical, Issue 24, 2019, Page(s) 102011, ISSN 2213-1582
DOI: 10.1016/j.nicl.2019.102011

Author(s): Lara Lordier, Djalel-Eddine Meskaldji, Frédéric Grouiller, Marie P. Pittet, Andreas Vollenweider, Lana Vasung, Cristina Borradori-Tolsa, François Lazeyras, Didier Grandjean, Dimitri Van De Ville, Petra S. Hüppi
Published in: Proceedings of the National Academy of Sciences, 2019, Page(s) 201817536, ISSN 0027-8424
DOI: 10.1073/pnas.1817536116

Author(s): Claire Cury, Marco Lorenzi, David Cash, Jennifer M. Nicholas, Alexandre Routier, Jonathan Rohrer, Sebastien Ourselin, Stanley Durrleman, Marc Modat
Published in: Springer, 2016, Page(s) 63-75, ISSN 0018-1560
DOI: 10.1007/978-3-319-51237-2_6

Published in: ISSN 1552-5260
DOI: 10.1016/j.jalz.2016.06.756

Published in: ISSN 1350-7540
DOI: 10.1097/WCO.0000000000000460

Author(s): I. Koval, J.-B. Schiratti, A. Routier, M. Bacci, O. Colliot, S. Allassonnière, S. Durrleman
Published in: Medical Image Computing and Computer Assisted Intervention − MICCAI 2017, Issue 10433, 2017, Page(s) 451-459
DOI: 10.1007/978-3-319-66182-7_52

Author(s): Alexandre Bône, Maxime Louis, Benoît Martin, Stanley Durrleman
Published in: Shape in Medical Imaging - International Workshop, ShapeMI 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 20, 2018, Proceedings, Issue 11167, 2018, Page(s) 3-13
DOI: 10.1007/978-3-030-04747-4_1

Author(s): Răzvan Valentin Marinescu, Arman Eshaghi, Marco Lorenzi, Alexandra L. Young, Neil P. Oxtoby, Sara Garbarino, Timothy J. Shakespeare, Sebastian J. Crutch, Daniel C. Alexander
Published in: Information Processing in Medical Imaging, Issue 10265, 2017, Page(s) 134-145
DOI: 10.1007/978-3-319-59050-9_11

Author(s): Manon Ansart, Stéphane Epelbaum, Geoffroy Gagliardi, Olivier Colliot, Didier Dormont, Bruno Dubois, Harald Hampel, Stanley Durrleman
Published in: Deep Learning in Medical Image Analysis and Multimodal Learning for Clinical Decision Support, Issue 10553, 2017, Page(s) 357-364
DOI: 10.1007/978-3-319-67558-9_41

Author(s): Alexandre Bône, Maxime Louis, Alexandre Routier, Jorge Samper, Michael Bacci, Benjamin Charlier, Olivier Colliot, Stanley Durrleman
Published in: Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics, Issue 10551, 2017, Page(s) 101-113
DOI: 10.1007/978-3-319-67675-3_10

Author(s): Vikram Venkatraghavan, Esther E. Bron, Wiro J. Niessen, Stefan Klein
Published in: Information Processing in Medical Imaging, Issue 10265, 2017, Page(s) 121-133
DOI: 10.1007/978-3-319-59050-9_10

Author(s): Răzvan V. Marinescu, Neil P. Oxtoby, Alexandra L. Young, Esther E. Bron, Arthur W. Toga, Michael W. Weiner, Frederik Barkhof, Nick C. Fox, Polina Golland, Stefan Klein, Daniel C. Alexander
Published in: Predictive Intelligence in Medicine - Second International Workshop, PRIME 2019, Held in Conjunction with MICCAI 2019, Shenzhen, China, October 13, 2019, Proceedings, Issue 11843, 2019, Page(s) 1-10
DOI: 10.1007/978-3-030-32281-6_1

Author(s): Vikram Venkatraghavan, Florian Dubost, Esther E. Bron, Wiro J. Niessen, Marleen de Bruijne, Stefan Klein
Published in: Information Processing in Medical Imaging - 26th International Conference, IPMI 2019, Hong Kong, China, June 2–7, 2019, Proceedings, Issue 11492, 2019, Page(s) 169-180
DOI: 10.1007/978-3-030-20351-1_13

Author(s): Maxime Louis, Raphaël Couronné, Igor Koval, Benjamin Charlier, Stanley Durrleman
Published in: Information Processing in Medical Imaging - 26th International Conference, IPMI 2019, Hong Kong, China, June 2–7, 2019, Proceedings, Issue 11492, 2019, Page(s) 542-553
DOI: 10.1007/978-3-030-20351-1_42

Author(s): Igor Koval, Alexandre Bône, Maxime Louis, Simona Bottani, Arnaud Marcoux, Jorge Samper-Gonzalez, Ninon Burgos, Benjamin Charlier, Anne Bertrand, Stéphane Epelbaum, Olivier Colliot, Stéphanie Allassonnière, Stanley Durrleman
Published in: 2018

Author(s): Alexandre Bone, Olivier Colliot, Stanley Durrleman
Published in: 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition, 2018, Page(s) 9271-9280
DOI: 10.1109/cvpr.2018.00966

Author(s): Jorge Samper-Gonzalez, Ninon Burgos, Simona Bottani, Marie-Odile Habert, Theodoros Evgeniou, Stephane Epelbaum, Olivier Colliot
Published in: Medical Imaging 2019: Image Processing, 2019, Page(s) 30
DOI: 10.1117/12.2512430

Author(s): Alexandre Bône, Olivier Colliot, Stanley Durrleman
Published in: 2019

Author(s): Alexandre Bône, Benoît Martin, Maxime Louis, Olivier Colliot, Stanley Durrleman
Published in: 2019

Author(s): Manon Ansart, Stéphane Epelbaum, Giulia Bassignana, Alexandre Bône, Simona Bottani, Tiziana Cattai, Raphael Couronne, Johann Faouzi, Igor Koval, Maxime Louis, et al.
Published in: 2019

Author(s): Alexandre Bône, Olivier Colliot, Stanley Durrleman
Published in: 2019

Author(s): Igor Koval, Stéphanie Allassonnière, Stanley Durrleman
Published in: 2019

Author(s): Marco Lorenzi, Maurizio Filippone, Daniel C. Alexander, Sebastien Ourselin
Published in: 2016

Author(s): Alexandre Bône, Maxime Louis, Alexandre Routier, Jorge Samper, Michael Bacci, Benjamin Charlier, Olivier Colliot, Stanley Durrleman
Published in: 2017