Endothelial long non-coding RNAs

Project Information

Angiolnc

Grant agreement ID: 667255

DOI

10.3030/667255

Project closed

EC signature date 26 October 2015

Start date 1 January 2016

End date 30 June 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 497 398,00

EU contribution

€ 2 497 398,00

Coordinated by

JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Clonal Hematopoiesis–Driver DNMT3A Mutations Alter Immune Cells in Heart Failure

Author(s): Wesley Tyler Abplanalp, Sebastian Cremer, David John, Jedrzej Hoffmann, Bianca Schuhmacher, Maximillian Merten, Michael A. Rieger, Mariuca Vasa-Nicotera, Andreas M. Zeiher, Stefanie Dimmeler
Published in: Circulation Research, Issue 128/2, 2021, Page(s) 216-228, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.120.317104

Noncoding RNAs in Vascular Diseases

Author(s): Nicolas Jaé, Stefanie Dimmeler
Published in: Circulation Research, Issue 126/9, 2020, Page(s) 1127-1145, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.315938

Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFRβ

Author(s): Zehendner CM, Valasarajan C, Werner A, Boeckel JN, Bischoff FC, John D, Weirick T, Glaser SF, Rossbach O, Jaé N, Demolli S, Khassafi F, Yuan K, de Jesus Perez VA, Michalik KM, Chen W, Seeger W, Guenther A, Wasnick RM, Uchida S, Zeiher AM, Dimmeler S, Pullamsetti SS
Published in: Am J Respir Crit Care Med., Issue 202(10), 2020, Page(s) 1445-1457., ISSN 1073-449X
Publisher: American Thoracic Society
DOI: 10.1164/rccm.201910-2041oc

Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in PericytesNovelty and Significance

Author(s): Florian C. Bischoff, Astrid Werner, David John, Jes-Niels Boeckel, Maria-Theodora Melissari, Phillip Grote, Simone F. Glaser, Shemsi Demolli, Shizuka Uchida, Katharina M. Michalik, Benjamin Meder, Hugo A. Katus, Jan Haas, Wei Chen, Soni S. Pullamsetti, Werner Seeger, Andreas M. Zeiher, Stefanie Dimmeler, Christoph M. Zehendner
Published in: Circulation Research, Issue 121/4, 2017, Page(s) 368-375, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.116.310531

The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2

Author(s): Philipp Neumann, Nicolas Jaé, Andrea Knau, Simone F. Glaser, Youssef Fouani, Oliver Rossbach, Marcus Krüger, David John, Albrecht Bindereif, Phillip Grote, Reinier A. Boon, Stefanie Dimmeler
Published in: Nature Communications, Issue 9/1, 2018, Page(s) all, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-02431-1

RNA Therapeutics in Cardiovascular Disease

Author(s): Tina Lucas, Angelika Bonauer, Stefanie Dimmeler
Published in: Circulation Research, Issue 123/2, 2018, Page(s) 205-220, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.117.311311

Hematopoietic Deficiency of the Long Non-Coding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation

Author(s): Sebastian Cremer, Katharina M. Michalik, Ariane Fischer, Larissa Pfisterer, Nicolas Jaé, Carla Winter, Reinier A. Boon, Marion Muhly-Reinholz, David John, Shizuka Uchida, Christian Weber, Wolfgang Poller, Stefan Günther, Thomas Braun, Daniel Y. Li, Lars Maegdefessel, Ljubica Matic Perisic, Ulf Hedin, Oliver Soehnlein, Andreas Zeiher, Stefanie Dimmeler
Published in: Circulation, 2018, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.117.029015

Deep Characterization of Circular RNAs from Human Cardiovascular Cell Models and Cardiac Tissue

Author(s): Jakobi T, Siede D, Eschenbach J, Heumüller AW, Busch M, Nietsch R, Meder B, Most P, Dimmeler S, Backs J, Katus HA, Dieterich C.
Published in: Cells, Issue 9(7), 2020, Page(s) 1616, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells9071616

Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses

Author(s): Heumüller AW, Jones AN, Mourão A, Klangwart M, Shi C, Wittig I, Fischer A, Muhly-Reinholz M, Buchmann GK, Dieterich C, Potente M, Braun T, Grote P, Jaé N, Sattler M, Dimmeler S.
Published in: Circulation Research, Issue 130, 2022, Page(s) 67-79, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.121.320029

Intellectual Property Rights

Patent (3)

PERICYTE LONG NON-CODING RNAS

Application/Publication number: EP 16710753
Date: 2016-03-18
Applicant(s): JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN

CIRCULAR RNA FOR THE DIAGNOSIS OF CARDIOVASCULAR AND INFLAMMATORY DISEASES

Application/Publication number: EP 16703505
Date: 2016-02-03
Applicant(s): JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN

LONG NON-CODING RNA FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION

Application/Publication number: EP 16703488
Date: 2016-02-03
Applicant(s): JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN