The interpretation of retinal activity by the visual thalamus.

Project Information

RETMUS

Grant agreement ID: 669157

DOI 10.3030/669157

Project closed

EC signature date 26 August 2015

Start date 1 November 2015

End date 31 October 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 500 000,00

EU contribution € 2 500 000,00

Coordinated by

INSTITUT FUR MOLEKULARE UND KLINISCHE OPHTHALMOLOGIE BASEL
Switzerland

Publications

Peer reviewed articles (11)

The first steps in vision: cell types, circuits, and repair

Author(s): Botond Roska
Published in: EMBO Molecular Medicine, Issue 11/3, 2019, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201810218

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

Author(s): Josephine Jüttner, Arnold Szabo, Brigitte Gross-Scherf, Rei K. Morikawa, Santiago B. Rompani, Peter Hantz, Tamas Szikra, Federico Esposti, Cameron S. Cowan, Arjun Bharioke, Claudia P. Patino-Alvarez, Özkan Keles, Akos Kusnyerik, Thierry Azoulay, Dominik Hartl, Arnaud R. Krebs, Dirk Schübeler, Rozina I. Hajdu, Akos Lukats, Janos Nemeth, Zoltan Z. Nagy, Kun-Chao Wu, Rong-Han Wu, Lue Xiang, Xiao-L
Published in: Nature Neuroscience, Issue 22/8, 2019, Page(s) 1345-1356, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-019-0431-2

Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex

Author(s): Daniel Hillier, Michele Fiscella, Antonia Drinnenberg, Stuart Trenholm, Santiago B Rompani, Zoltan Raics, Gergely Katona, Josephine Juettner, Andreas Hierlemann, Balazs Rozsa, Botond Roska
Published in: Nature Neuroscience, Issue 20/7, 2017, Page(s) 960-968, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/nn.4566

Restoring light sensitivity using tunable near-infrared sensors

Author(s): Dasha Nelidova, Rei K. Morikawa, Cameron S. Cowan, Zoltan Raics, David Goldblum, Hendrik P. N. Scholl, Tamas Szikra, Arnold Szabo, Daniel Hillier, Botond Roska
Published in: Science, Issue 368/6495, 2020, Page(s) 1108-1113, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aaz5887

Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity

Author(s): Keisuke Yonehara, Michele Fiscella, Antonia Drinnenberg, Federico Esposti, Stuart Trenholm, Jacek Krol, Felix Franke, Brigitte Gross Scherf, Akos Kusnyerik, Jan Müller, Arnold Szabo, Josephine Jüttner, Francisco Cordoba, Ashrithpal Police Reddy, János Németh, Zoltán Zsolt Nagy, Francis Munier, Andreas Hierlemann, Botond Roska
Published in: Neuron, Issue 89/1, 2016, Page(s) 177-193, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2015.11.032

The formation of the light-sensing compartment of cone photoreceptors coincides with a transcriptional switch

Author(s): Janine M Daum, Özkan Keles, Sjoerd JB Holwerda, Hubertus Kohler, Filippo M Rijli, Michael Stadler, Botond Roska
Published in: eLife, Issue 6, 2017, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.31437

Whole-Brain Functional Ultrasound Imaging Reveals Brain Modules for Visuomotor Integration

Author(s): Émilie Macé, Gabriel Montaldo, Stuart Trenholm, Cameron Cowan, Alexandra Brignall, Alan Urban, Botond Roska
Published in: Neuron, Issue 100/5, 2018, Page(s) 1241-1251.e7, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2018.11.031

Virus stamping for targeted single-cell infection in vitro and in vivo

Author(s): Rajib Schubert, Stuart Trenholm, Kamill Balint, Georg Kosche, Cameron S Cowan, Manuel A Mohr, Martin Munz, David Martinez-Martin, Gotthold Fläschner, Richard Newton, Jacek Krol, Brigitte Gross Scherf, Keisuke Yonehara, Adrian Wertz, Aaron Ponti, Alexander Ghanem, Daniel Hillier, Karl-Klaus Conzelmann, Daniel J Müller, Botond Roska
Published in: Nature Biotechnology, Issue 36/1, 2017, Page(s) 81-88, ISSN 1087-0156
Publisher: Nature Publishing Group
DOI: 10.1038/nbt.4034

Different Modes of Visual Integration in the Lateral Geniculate Nucleus Revealed by Single-Cell-Initiated Transsynaptic Tracing

Author(s): Santiago B. Rompani, Fiona E. Müllner, Adrian Wanner, Chi Zhang, Chiara N. Roth, Keisuke Yonehara, Botond Roska
Published in: Neuron, Issue 93/4, 2017, Page(s) 767-776.e6, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2017.01.028

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

Author(s): Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, Brigitte Gross-Scherf, David Goldblum, Yanyan Hou, Martin Munz, Tiago M. Rodrigues, Jacek Krol, Tamas Szikra, Rachel Cuttat, Annick Waldt, Panagiotis Papasaikas, Roland Diggelmann, Claudia P. Patino-Alvarez, Patricia Galliker, Stefan E. Spirig, Dinko Pavlinic, Nadine Gerber-Hollbach, Sven Schuierer, Aldin Srdanovic, Marton Balogh, Riccardo Pa
Published in: Cell, Issue 182/6, 2020, Page(s) 1623-1640.e34, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2020.08.013

How Diverse Retinal Functions Arise from Feedback at the First Visual Synapse

Author(s): Antonia Drinnenberg, Felix Franke, Rei K. Morikawa, Josephine Jüttner, Daniel Hillier, Peter Hantz, Andreas Hierlemann, Rava Azeredo da Silveira, Botond Roska
Published in: Neuron, Issue 99/1, 2018, Page(s) 117-134.e11, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2018.06.001

Intellectual Property Rights

Patent (17)

SYNP161, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS

Application/Publication number: 16 809182
Date: 2016-12-01
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

PROMOTERS AND USES THEREOF

Application/Publication number: 16 806078
Date: 2016-12-05
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNP160, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS

Application/Publication number: 16 809181
Date: 2016-12-01
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

PRIMATE RETINAL PIGMENT EPITHELIUM CELL-SPECIFIC PROMOTER

Application/Publication number: 18 808513
Date: 2018-11-15
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SynP61, A PRIMATE RETINAL PIGMENT EPITHELIUM CELL-SPECIFIC PROMOTER

Application/Publication number: 18 833620
Date: 2018-11-28
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

NOVEL THERAPEUTIC TOOLS AND METHODS FOR TREATING BLINDNESS

Application/Publication number: 17 725361
Date: 2017-05-15
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNP88, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN RETINAL GANGLION CELLS

Application/Publication number: 18 704314
Date: 2018-02-05
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNP198, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN DIRECTION SELECTIVE RETINAL GANGLION CELLS

Application/Publication number: 17 811378
Date: 2017-11-01
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

NOVEL THERAPEUTICAL TOOLS AND METHODS FOR TREATING BLINDNESS BY TARGETING PHOTORECEPTORS

Application/Publication number: 16 770708
Date: 2016-09-13
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNPI, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN INTERNEURONS

Application/Publication number: 17 816564
Date: 2017-11-29
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNP107, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN INTERNEURONS

Application/Publication number: 17 816563
Date: 2017-11-29
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNP162, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS

Application/Publication number: 16 809183
Date: 2016-12-01
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

NOVEL METHODS FOR THE TARGETED INTRODUCTION OF VIRUSES INTO CELLS

Application/Publication number: 14 706119
Date: 2014-02-06
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNP157, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS

Application/Publication number: 15 197895
Date: 2015-12-03
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN RETINAL ENDOTHELIAL CELLS

Application/Publication number: 16 788240
Date: 2016-10-13
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNPIII, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN RETINAL PIGMENT EPITHELIUM

Application/Publication number: 18 833621
Date: 2018-11-28
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION

SYNP159, A PROMOTER FOR THE SPECIFIC EXPRESSION OF GENES IN ROD PHOTORECEPTORS

Application/Publication number: 16 809180
Date: 2016-12-01
Applicant(s): FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION