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Exoribonuclease-mediated degradation of nascent RNA in Malaria Parasites: A Novel Mechanism in Virulence Gene Silencing

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A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

Author(s): Gigliola Zanghì, Shruthi S. Vembar, Sebastian Baumgarten, Shuai Ding, Julien Guizetti, Jessica M. Bryant, Denise Mattei, Anja T.R. Jensen, Laurent Rénia, Yun Shan Goh, Robert Sauerwein, Cornelus C. Hermsen, Jean-François Franetich, Mallaury Bordessoulles, Olivier Silvie, Valérie Soulard, Olivier Scatton, Patty Chen, Salah Mecheri, Dominique Mazier, Artur Scherf
Published in: Cell Reports, Issue 22/11, 2018, Page(s) 2951-2963, ISSN 2211-1247
DOI: 10.1016/j.celrep.2018.02.075

Translational regulation in blood stages of the malaria parasite Plasmodium spp. : systems-wide studies pave the way

Author(s): Shruthi Sridhar Vembar, Dorothea Droll, Artur Scherf
Published in: Wiley Interdisciplinary Reviews: RNA, Issue 7/6, 2016, Page(s) 772-792, ISSN 1757-7004
DOI: 10.1002/wrna.1365

Complete telomere-to-telomere de novo assembly of the Plasmodium falciparum genome through long-read (>11 kb), single molecule, real-time sequencing

Author(s): Shruthi Sridhar Vembar, Matthew Seetin, Christine Lambert, Maria Nattestad, Michael C. Schatz, Primo Baybayan, Artur Scherf, Melissa Laird Smith
Published in: DNA Research, Issue 23/4, 2016, Page(s) 339-351, ISSN 1340-2838
DOI: 10.1093/dnares/dsw022

De Novo Genome Assembly of a Plasmodium falciparum NF54 Clone Using Single-Molecule Real-Time Sequencing

Author(s): Jessica M. Bryant, Sebastian Baumgarten, Audrey Lorthiois, Christine Scheidig-Benatar, Aurélie Claës, Artur Scherf
Published in: Genome Announcements, Issue 6/5, 2018, ISSN 2169-8287
DOI: 10.1128/genomeA.01479-17

An ApiAP2 member regulates expression of clonally variant genes of the human malaria parasite Plasmodium falciparum

Author(s): Rafael M. Martins, Cameron R. Macpherson, Aurélie Claes, Christine Scheidig-Benatar, Hiroshi Sakamoto, Xue Yan Yam, Peter Preiser, Suchi Goel, Mats Wahlgren, Odile Sismeiro, Jean-Yves Coppée, Artur Scherf
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
DOI: 10.1038/s41598-017-12578-y

Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites

Author(s): Fabien Sindikubwabo, Shuai Ding, Tahir Hussain, Philippe Ortet, Mohamed Barakat, Sebastian Baumgarten, Dominique Cannella, Andrés Palencia, Alexandre Bougdour, Lucid Belmudes, Yohann Couté, Isabelle Tardieux, Cyrille Y Botté, Artur Scherf, Mohamed-ali Hakimi
Published in: eLife, Issue 6, 2017, ISSN 2050-084X
DOI: 10.7554/eLife.29391

Trans-acting GC-rich non-coding RNA at var expression site modulates gene counting in malaria parasite

Author(s): Julien Guizetti, Anna Barcons-Simon, Artur Scherf
Published in: Nucleic Acids Research, 2016, Page(s) gkw664, ISSN 0305-1048
DOI: 10.1093/nar/gkw664

CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum

Author(s): Jessica M. Bryant, Clément Regnault, Christine Scheidig-Benatar, Sebastian Baumgarten, Julien Guizetti, Artur Scherf
Published in: mBio, Issue 8/4, 2017, ISSN 2150-7511
DOI: 10.1128/mBio.00729-17

Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development

Author(s): Sebastian Baumgarten, Jessica M. Bryant, Ameya Sinha, Thibaud Reyser, Peter R. Preiser, Peter C. Dedon, Artur Scherf
Published in: Nature Microbiology, Issue 4/12, 2019, Page(s) 2246-2259, ISSN 2058-5276
DOI: 10.1038/s41564-019-0521-7

Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites

Author(s): Elie Hammam, Guruprasad Ananda, Ameya Sinha, Christine Scheidig-Benatar, Mylene Bohec, Peter R Preiser, Peter C Dedon, Artur Scherf, Shruthi S Vembar
Published in: Nucleic Acids Research, Issue 48/1, 2019, Page(s) 184-199, ISSN 0305-1048
DOI: 10.1093/nar/gkz1093

DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites

Author(s): Flore Nardella, Ludovic Halby, Elie Hammam, Diane Erdmann, Véronique Cadet-Daniel, Roger Peronet, Didier Ménard, Benoit Witkowski, Salah Mecheri, Artur Scherf, Paola B. Arimondo
Published in: ACS Central Science, Issue 6/1, 2020, Page(s) 16-21, ISSN 2374-7943
DOI: 10.1021/acscentsci.9b00874

Clipped histone H3 is integrated into nucleosomes of DNA replication genes in the human malaria parasite Plasmodium falciparum

Author(s): Abril Marcela Herrera‐Solorio, Shruthi Sridhar Vembar, Cameron Ross MacPherson, Daniela Lozano‐Amado, Gabriela Romero Meza, Beatriz Xoconostle‐Cazares, Rafael Miyazawa Martins, Patty Chen, Miguel Vargas, Artur Scherf, Rosaura Hernández‐Rivas
Published in: EMBO reports, Issue 20/4, 2019, ISSN 1469-221X
DOI: 10.15252/embr.201846331

Disruption of the RNA exosome reveals the hidden face of the malaria parasite transcriptome

Author(s): Dorothea Droll, Guiying Wei, Gangqiang Guo, Yanting Fan, Sebastian Baumgarten, Yiqing Zhou, Youli Xiao, Artur Scherf, Qingfeng Zhang
Published in: RNA Biology, Issue 15/9, 2018, Page(s) 1206-1214, ISSN 1547-6286
DOI: 10.1080/15476286.2018.1517014

Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites

Author(s): Patty B. Chen, Shuai Ding, Gigliola Zanghì, Valérie Soulard, Peter A. DiMaggio, Matthew J. Fuchter, Salah Mecheri, Dominique Mazier, Artur Scherf, Nicholas A. Malmquist
Published in: Scientific Reports, Issue 6/1, 2016, ISSN 2045-2322
DOI: 10.1038/srep21802

Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species

Author(s): Roger Cubi, Shruthi S. Vembar, Anne Biton, Jean-Francois Franetich, Mallaury Bordessoulles, Daniel Sossau, Gigliola Zanghi, Henriette Bosson-Vanga, Magalie Benard, Alicia Moreno, Nathalie Dereuddre-Bosquet, Roger Le Grand, Artur Scherf, Dominique Mazier
Published in: Cellular Microbiology, Issue 19/8, 2017, Page(s) e12735, ISSN 1462-5814
DOI: 10.1111/cmi.12735

CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum

Author(s): Anna Barcons-Simon, Carlos Cordon-Obras, Julien Guizetti, Jessica M. Bryant, Artur Scherf
Published in: mBio, Issue 11/1, 2020, ISSN 2150-7511
DOI: 10.1128/mBio.03054-19