Bacterial, cellular and epigenetic factors that control enteropathogenicity

Project Information

BacCellEpi

Grant agreement ID: 670823

DOI 10.3030/670823

Project closed

EC signature date 23 September 2015

Start date 1 October 2015

End date 30 September 2019

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 147 500,00

EU contribution € 1 147 500,00

Coordinated by

INSTITUT PASTEUR
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (27)

Listeriolysin O-dependent host surfaceome remodeling modulates Listeria monocytogenes invasion

Author(s): Andreas Kühbacher, Karel Novy, Juan J Quereda, Martin Sachse, Maryse Moya-Nilges, Bernd Wollscheid, Pascale Cossart, Javier Pizarro-Cerdá
Published in: Pathogens and Disease, Issue 76/8, 2018, ISSN 2049-632X
Publisher: John Wiley & Sons Inc.
DOI: 10.1093/femspd/fty082

Infection Reveals a Modification of SIRT2 Critical for Chromatin Association

Author(s): Jorge M. Pereira, Christine Chevalier, Thibault Chaze, Quentin Gianetto, Francis Impens, Mariette Matondo, Pascale Cossart, Mélanie A. Hamon
Published in: Cell Reports, Issue 23/4, 2018, Page(s) 1124-1137, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2018.03.116

N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes

Author(s): Francis Impens, Nathalie Rolhion, Lilliana Radoshevich, Christophe Bécavin, Mélodie Duval, Jeffrey Mellin, Francisco García del Portillo, M. Graciela Pucciarelli, Allison H. Williams, Pascale Cossart
Published in: Nature Microbiology, Issue 2, 2017, Page(s) 17005, ISSN 2058-5276
Publisher: nature microbiology
DOI: 10.1038/nmicrobiol.2017.5

Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria

Author(s): D. Dar, M. Shamir, J. R. Mellin, M. Koutero, N. Stern-Ginossar, P. Cossart, R. Sorek
Published in: Science, Issue 352/6282, 2016, Page(s) aad9822-aad9822, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aad9822

Listeriomics: an Interactive Web Platform for Systems Biology of Listeria

Author(s): Christophe Bécavin, Mikael Koutero, Nicolas Tchitchek, Franck Cerutti, Pierre Lechat, Nicolas Maillet, Claire Hoede, Hélène Chiapello, Christine Gaspin, Pascale Cossart
Published in: mSystems, Issue 2/2, 2017, Page(s) e00186-16, ISSN 2379-5077
Publisher: ASM Press
DOI: 10.1128/mSystems.00186-16

Bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection

Author(s): Juan J. Quereda, Olivier Dussurget, Marie-Anne Nahori, Amine Ghozlane, Stevenn Volant, Marie-Agnès Dillies, Béatrice Regnault, Sean Kennedy, Stanislas Mondot, Barbara Villoing, Pascale Cossart, Javier Pizarro-Cerda
Published in: Proceedings of the National Academy of Sciences, Issue 113/20, 2016, Page(s) 5706-5711, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1523899113

A role for septin 2 in Drp1‐mediated mitochondrial fission

Author(s): Alessandro Pagliuso, To Nam Tham, Julia K Stevens, Thibault Lagache, Roger Persson, Audrey Salles, Jean‐Christophe Olivo‐Marin, Stéphane Oddos, Anne Spang, Pascale Cossart, Fabrizia Stavru
Published in: EMBO reports, Issue 17/6, 2016, Page(s) 858-873, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.201541612

Listeriolysin S Is a Streptolysin S-Like Virulence Factor That Targets Exclusively Prokaryotic Cells In Vivo

Author(s): Juan J. Quereda, Marie A. Nahori, Jazmín Meza-Torres, Martin Sachse, Patricia Titos-Jiménez, Jaime Gomez-Laguna, Olivier Dussurget, Pascale Cossart, Javier Pizarro-Cerdá
Published in: mBio, Issue 8/2, 2017, Page(s) e00259-17, ISSN 2150-7511
Publisher: ASM Press
DOI: 10.1128/mBio.00259-17

The ever-growing complexity of the mitochondrial fission machinery

Author(s): Alessandro Pagliuso, Pascale Cossart, Fabrizia Stavru
Published in: Cellular and Molecular Life Sciences, Issue 75/3, 2018, Page(s) 355-374, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-017-2603-0

SUMOylation of human septins is critical for septin filament bundling and cytokinesis

Author(s): David Ribet, Serena Boscaini, Clothilde Cauvin, Martin Siguier, Serge Mostowy, Arnaud Echard, Pascale Cossart
Published in: The Journal of Cell Biology, Issue 216/12, 2017, Page(s) 4041-4052, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.201703096

Reassessing the role of internalin B in Listeria monocytogenes virulence using the epidemic strain F2365

Author(s): J.J. Quereda, I.M. Rodríguez-Gómez, J. Meza-Torres, J. Gómez-Laguna, M.A. Nahori, O. Dussurget, L. Carrasco, P. Cossart, J. Pizarro-Cerdá
Published in: Clinical Microbiology and Infection, Issue 25/2, 2019, Page(s) 252.e1-252.e4, ISSN 1198-743X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2018.08.022

The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation

Author(s): Allison H. Williams, Adam Redzej, Nathalie Rolhion, Tiago R. D. Costa, Aline Rifflet, Gabriel Waksman, Pascale Cossart
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-10782-0

Overexpression of the Heterochromatinization Factor BAHD1 in HEK293 Cells Differentially Reshapes the DNA Methylome on Autosomes and X Chromosome

Author(s): Emanuele Libertini, Alice Lebreton, Goran Lakisic, Marie-Agnès Dillies, Stephan Beck, Jean-Yves Coppée, Pascale Cossart, Hélène Bierne
Published in: Frontiers in Genetics, Issue 6, 2015, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2015.00339

How the study of Listeria monocytogenes has led to new concepts in biology

Author(s): Nathalie Rolhion, Pascale Cossart
Published in: Future Microbiology, Issue 12/7, 2017, Page(s) 621-638, ISSN 1746-0913
Publisher: Future Medicine Ltd.
DOI: 10.2217/fmb-2016-0221

A Lasting Impression: Epigenetic Memory of Bacterial Infections?

Author(s): Jorge M. Pereira, Mélanie A. Hamon, Pascale Cossart
Published in: Cell Host & Microbe, Issue 19/5, 2016, Page(s) 579-582, ISSN 1931-3128
Publisher: Cell Press
DOI: 10.1016/j.chom.2016.04.012

Role in virulence of phospholipases, listeriolysin O and listeriolysin S from epidemic Listeria monocytogenes using the chicken embryo infection model

Author(s): Juan J. Quereda, Christopher Andersson, Pascale Cossart, Jörgen Johansson, Javier Pizarro-Cerdá
Published in: Veterinary Research, Issue 49/1, 2018, ISSN 1297-9716
Publisher: Springer
DOI: 10.1186/s13567-017-0496-4

Lmo1656 is a secreted virulence factor of Listeria monocytogenes that interacts with the sorting nexin 6–BAR complex

Author(s): Daryl Jason David, Alessandro Pagliuso, Lilliana Radoshevich, Marie-Anne Nahori, Pascale Cossart
Published in: Journal of Biological Chemistry, Issue 293/24, 2018, Page(s) 9265-9276, ISSN 0021-9258
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.RA117.000365

OrfX, a Nucleomodulin Required for Listeria monocytogenes Virulence

Author(s): Andrzej Prokop, Edith Gouin, Véronique Villiers, Marie-Anne Nahori, Renaud Vincentelli, Mélodie Duval, Pascale Cossart, Olivier Dussurget
Published in: mBio, Issue 8/5, 2017, ISSN 2150-7511
Publisher: ASM Press
DOI: 10.1128/mBio.01550-17

Small bacterial and phagic proteins: an updated view on a rapidly moving field

Author(s): Mélodie Duval, Pascale Cossart
Published in: Current Opinion in Microbiology, Issue 39, 2017, Page(s) 81-88, ISSN 1369-5274
Publisher: Elsevier BV
DOI: 10.1016/j.mib.2017.09.010

Ubiquitin, SUMO, and NEDD8: Key Targets of Bacterial Pathogens

Author(s): David Ribet, Pascale Cossart
Published in: Trends in Cell Biology, Issue 28/11, 2018, Page(s) 926-940, ISSN 0962-8924
Publisher: Elsevier BV
DOI: 10.1016/j.tcb.2018.07.005

Listeria monocytogenes: towards a complete picture of its physiology and pathogenesis

Author(s): Lilliana Radoshevich, Pascale Cossart
Published in: Nature Reviews Microbiology, Issue 16/1, 2018, Page(s) 32-46, ISSN 1740-1526
Publisher: Nature Publishing Group
DOI: 10.1038/nrmicro.2017.126

A Dual Microscopy-Based Assay To Assess Listeria monocytogenes Cellular Entry and Vacuolar Escape

Author(s): Juan J. Quereda, Javier Pizarro-Cerdá, Damien Balestrino, Alexandre Bobard, Anne Danckaert, Nathalie Aulner, Spencer Shorte, Jost Enninga, Pascale Cossart
Published in: Applied and Environmental Microbiology, Issue 82/1, 2015, Page(s) 211-217, ISSN 0099-2240
Publisher: American Society for Microbiology
DOI: 10.1128/AEM.02302-15

Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism

Author(s): Goran Lakisic, Alice Lebreton, Renaud Pourpre, Olivia Wendling, Emanuele Libertini, Elizabeth J. Radford, Morwenna Le Guillou, Marie-France Champy, Marie Wattenhofer-Donzé, Guillaume Soubigou, Slimane Ait-Si-Ali, Jean Feunteun, Tania Sorg, Jean-Yves Coppée, Anne C. Ferguson-Smith, Pascale Cossart, Hélène Bierne
Published in: PLOS Genetics, Issue 12/3, 2016, Page(s) e1005898, ISSN 1553-7404
Publisher: PLOS Genetics
DOI: 10.1371/journal.pgen.1005898

Alteration of epithelial cell lysosomal integrity induced by bacterial cholesterol-dependent cytolysins

Author(s): Julien Karim Malet, Pascale Cossart, David Ribet
Published in: Cellular Microbiology, Issue 19/4, 2017, Page(s) e12682, ISSN 1462-5814
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cmi.12682

RNA- and protein-mediated control of Listeria monocytogenes virulence gene expression

Author(s): Alice Lebreton, Pascale Cossart
Published in: RNA Biology, Issue 14/5, 2016, Page(s) 460-470, ISSN 1547-6286
Publisher: Landes Bioscience
DOI: 10.1080/15476286.2016.1189069

Listeriolysin S: A bacteriocin from epidemic Listeria monocytogenes strains that targets the gut microbiota

Author(s): Juan J. Quereda, Jazmín Meza-Torres, Pascale Cossart, Javier Pizarro-Cerdá
Published in: Gut Microbes, 2017, Page(s) 1-8, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2017.1290759

Promyelocytic Leukemia Protein (PML) Controls Listeria monocytogenes Infection

Author(s): David Ribet, Valérie Lallemand-Breitenbach, Omar Ferhi, Marie-Anne Nahori, Hugo Varet, Hugues de Thé, Pascale Cossart
Published in: mBio, Issue 8/1, 2017, Page(s) e02179-16, ISSN 2150-7511
Publisher: ASM
DOI: 10.1128/mBio.02179-16

Monographic books (1)

Regulating Bacterial Virulence with RNA

Author(s): Quereda , Juan; Cossart , Pascale
Published in: Annual Review of Microbiology, Issue 2, 2017, Page(s) 263-280
Publisher: Annual Reviews
DOI: 10.1146/annurev-micro-030117-020335

Book chapters (1)

Assessing Vacuolar Escape of Listeria Monocytogenes

Author(s): Juan J. Quereda, Martin Sachse, Damien Balestrino, Théodore Grenier, Jennifer Fredlund, Anne Danckaert, Nathalie Aulner, Spencer Shorte, Jost Enninga, Pascale Cossart, Javier Pizarro-Cerdá
Published in: Methods in Molecular Biology, 2017, Page(s) 173-195
Publisher: Springer New York
DOI: 10.1007/978-1-4939-6673-8_11

Intellectual Property Rights

Patent (2)

LISTERIOLYSIN S OR RELATED PEPTIDES AS ANTIBACTERIALS

Application/Publication number: 16 305292
Date: 2016-03-16
Applicant(s): INSTITUT PASTEUR

ANTI-PREVOTELLA BACTERIOCIN METHODS AND COMPOSITIONS

Application/Publication number: 20 19053170
Date: 2019-02-08
Applicant(s): INSTITUT PASTEUR