Nanopore sensing has a broad range of potential applications (e.g. detection of trace amounts of substances in drug delivery/cancer diagnosis/tests for nanotoxicity and infectious diseases, next generation of DNA sequencing and protein fingerprinting) due to its outstanding sensitivity for label-free single molecule analysis. The lack of a reliable high throughput fabrication process for uniformly sized nanopores has become a serious bottleneck for research, industry and economy. Within a feasibility study in the frame of the SME-Instrument Phase I programme, Ionera has combined a nano-fabrication process recently developed on a laboratory scale with its proprietary MECA technology platform and delivered the proof of principle for a parallel, industrially applicable fabrication of solid state nanopores. This was accompanied by an assessment of the economic viability of a high throughput platform for in situ nanopore fabrication and analysis.