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Plug and play enzymes for an accelerated uptake of Biocatalysis in the Pharmaceutical Industry

Deliverables

Publications

Three in One: Temperature, Solvent and Catalytic Stability by Engineering the Cofactor-Binding Element of Amine Transaminase

Author(s): Tim Börner, Sebastian Rämisch, Sebastian Bartsch, Andreas Vogel, Patrick Adlercreutz, Carl Grey
Published in: ChemBioChem, Issue 18/15, 2017, Page(s) 1482-1486, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201700236

A Chemoenzymatic Route to Chiral Intermediates Used in the Multikilogram Synthesis of a Gamma Secretase Inhibitor

Author(s): Michael Burns, Carlos A. Martinez, Brian Vanderplas, Richard Wisdom, Shu Yu, Robert A. Singer
Published in: Organic Process Research & Development, Issue 21/6, 2017, Page(s) 871-877, ISSN 1083-6160
Publisher: American Chemical Society
DOI: 10.1021/acs.oprd.7b00096

Synthesis of Sebacic Acid Using a De Novo Designed Retro-Aldolase as a Key Catalyst

Author(s): Konrad B. Otte, Elena Maurer, Marko Kirtz, Daniela Grabs, Eric Althoff, Sebastian Bartsch, Andreas Vogel, Bettina M. Nestl, Bernhard Hauer
Published in: ChemCatChem, Issue 9/8, 2017, Page(s) 1378-1382, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201601551

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