Plug and play enzymes for an accelerated uptake of Biocatalysis in the Pharmaceutical Industry

Project Information

PlugBioIn

Grant agreement ID: 674200

DOI 10.3030/674200

Project closed

EC signature date 18 June 2015

Start date 1 January 2015

End date 30 June 2017

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology

Total cost € 681 125,00

EU contribution € 476 787,50

Coordinated by

C-LECTA GMBH
Germany

Deliverables

Websites, patent fillings, videos etc. (2)

Webinar on enzyme platform
Website for online ordering

Publications

Peer reviewed articles (3)

Three in One: Temperature, Solvent and Catalytic Stability by Engineering the Cofactor-Binding Element of Amine Transaminase

Author(s): Tim Börner, Sebastian Rämisch, Sebastian Bartsch, Andreas Vogel, Patrick Adlercreutz, Carl Grey
Published in: ChemBioChem, Issue 18/15, 2017, Page(s) 1482-1486, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201700236

A Chemoenzymatic Route to Chiral Intermediates Used in the Multikilogram Synthesis of a Gamma Secretase Inhibitor

Author(s): Michael Burns, Carlos A. Martinez, Brian Vanderplas, Richard Wisdom, Shu Yu, Robert A. Singer
Published in: Organic Process Research & Development, Issue 21/6, 2017, Page(s) 871-877, ISSN 1083-6160
Publisher: American Chemical Society
DOI: 10.1021/acs.oprd.7b00096

Synthesis of Sebacic Acid Using a De Novo Designed Retro-Aldolase as a Key Catalyst

Author(s): Konrad B. Otte, Elena Maurer, Marko Kirtz, Daniela Grabs, Eric Althoff, Sebastian Bartsch, Andreas Vogel, Bettina M. Nestl, Bernhard Hauer
Published in: ChemCatChem, Issue 9/8, 2017, Page(s) 1378-1382, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201601551