Combined Chemo- and Radiotherapies by Controlling the Surface Chemistry of Truncated Metal Organic Framework Nanoparticles

Project Information

SCoTMOF

Grant agreement ID: 677289

DOI

10.3030/677289

Project closed

EC signature date 28 April 2016

Start date 1 September 2016

End date 31 August 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 493 777,00

EU contribution

€ 1 493 777,00

Coordinated by

UNIVERSITY OF GLASGOW
United Kingdom

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (16)

Glycopolymer-Functionalized MOF-808 Nanoparticles as a Cancer-Targeted Dual Drug Delivery System for Carboplatin and Floxuridine

Author(s): Fatma Demir Duman, Alessandra Monaco, Rachel Foulkes, C. Remzi Becer, and Ross S. Forgan
Published in: ACS Applied Nanomaterials, Issue 5, 10, 2022, Page(s) 13862–13873, ISSN 2574-0970
Publisher: American Chemical Society
DOI: 10.1021/acsanm.2c01632

How Reproducible are Surface Areas Calculated from the BET Equation?

Author(s): Johannes W. M. Osterrieth, James Rampersad, David Madden, Nakul Rampal, Luka Skoric, Bethany Connolly, Mark D. Allendorf, Vitalie Stavila, Jonathan L. Snider, Rob Ameloot, João Marreiros, Conchi Ania, Diana Azevedo, Enrique Vilarrasa-Garcia, Bianca F. Santos, Xian-He Bu, Ze Chang, Hana Bunzen, Neil R. Champness, Sarah L. Griffin, Banglin Chen, Rui-Biao Lin, Benoit Coasne, Seth Cohen, Jessica C. M
Published in: Advanced Materials, Issue 34, 27, 2022, Page(s) 2201502, ISSN 1521-4095
Publisher: Wiley Interscience
DOI: 10.1002/adma.202201502

Modulated self-assembly of an interpenetrated MIL-53 Sc metal–organic framework with excellent volumetric H2 storage and working capacity

Author(s): Alexander J. R. Thom, David G. Madden, Rocio Bueno-Perez, Ali N. Al Shakhs, Ciaran T. Lennon, Ross J. Marshall, Catherine A. Walshe, Claire Wilson, Claire A. Murray, Stephen P. Thompson, Gemma F. Turner, Dominic Bara, Stephen A. Moggach, David Fairen-Jimenez and Ross S. Forgan
Published in: Materials Today Chemistry, Issue 24, 2022, Page(s) 100877, ISSN 2468-5194
Publisher: Elsevier
DOI: 10.1016/j.mtchem.2022.100887

Identifying Differing Intracellular Cargo Release Mechanisms by Monitoring In Vitro Drug Delivery from MOFs in Real Time

Author(s): Panagiota Markopoulou, Nikolaos Panagiotou, Aurelia Li, Rocio Bueno-Perez, David Madden, Sarah Buchanan, David Fairen-Jimenez, Paul G. Shiels, Ross S. Forgan
Published in: Cell Reports Physical Science, Issue 1/11, 2020, Page(s) 100254, ISSN 2666-3864
Publisher: Cell Press
DOI: 10.1016/j.xcrp.2020.100254

Applications of nanoscale metal–organic frameworks as imaging agents in biology and medicine

Author(s): Fatma Demir Duman, Ross S. Forgan
Published in: Journal of Materials Chemistry B, Issue Advance article, 2021, Page(s) 9, 3423–3449, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1tb00358e

Mechanistic Investigation into the Selective Anticancer Cytotoxicity and Immune System Response of Surface-Functionalized, Dichloroacetate-Loaded, UiO-66 Nanoparticles

Author(s): Isabel Abánades Lázaro, Salame Haddad, José M. Rodrigo-Muñoz, Claudia Orellana-Tavra, Victoria del Pozo, David Fairen-Jimenez, Ross S. Forgan
Published in: ACS Applied Materials & Interfaces, Issue 10/6, 2018, Page(s) 5255-5268, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.7b17756

Selective Surface PEGylation of UiO-66 Nanoparticles for Enhanced Stability, Cell Uptake, and pH-Responsive Drug Delivery

Author(s): Isabel Abánades Lázaro, Salame Haddad, Sabrina Sacca, Claudia Orellana-Tavra, David Fairen-Jimenez, Ross S. Forgan
Published in: Chem, Issue 2/4, 2017, Page(s) 561-578, ISSN 2451-9294
Publisher: Cell Press
DOI: 10.1016/j.chempr.2017.02.005

Controlling interpenetration through linker conformation in the modulated synthesis of Sc metal–organic frameworks

Author(s): Ross J. Marshall, Ciaran T. Lennon, Andi Tao, Hans M. Senn, Claire Wilson, David Fairen-Jimenez, Ross S. Forgan
Published in: Journal of Materials Chemistry A, Issue 6/3, 2018, Page(s) 1181-1187, ISSN 2050-7488
Publisher: Royal Society of Chemistry
DOI: 10.1039/C7TA09699B

Surface-Functionalization of Zr-Fumarate MOF for Selective Cytotoxicity and Immune System Compatibility in Nanoscale Drug Delivery

Author(s): Isabel Abánades Lázaro, Salame Haddad, Jose M. Rodrigo-Muñoz, Ross J. Marshall, Beatriz Sastre, Victoria del Pozo, David Fairen-Jimenez, Ross S. Forgan
Published in: ACS Applied Materials & Interfaces, Issue 10/37, 2018, Page(s) 31146-31157, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.8b11652

Kinetic Control of Interpenetration in Fe–Biphenyl-4,4′-dicarboxylate Metal–Organic Frameworks by Coordination and Oxidation Modulation

Author(s): Dominic Bara, Claire Wilson, Max Mörtel, Marat M. Khusniyarov, Sanliang Ling, Ben Slater, Stephen Sproules, Ross S. Forgan
Published in: Journal of the American Chemical Society, Issue 141, 2019, Page(s) 8346-8357, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.9b03269

Application of zirconium MOFs in drug delivery and biomedicine

Author(s): Isabel Abánades Lázaro, Ross S. Forgan
Published in: Coordination Chemistry Reviews, Issue 380, 2019, Page(s) 230-259, ISSN 0010-8545
Publisher: Elsevier BV
DOI: 10.1016/j.ccr.2018.09.009

Design of a Functionalized Metal–Organic Framework System for Enhanced Targeted Delivery to Mitochondria

Author(s): Salame Haddad, Isabel Abánades Lázaro, Marcus Fantham, Ajay Mishra, Joaquin Silvestre-Albero, Johannes W. M. Osterrieth, Gabriele S. Kaminski Schierle, Clemens F. Kaminski, Ross S. Forgan, David Fairen-Jimenez
Published in: Journal of the American Chemical Society, Issue 142/14, 2020, Page(s) 6661-6674, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c00188

Multivariate Modulation of the Zr MOF UiO‐66 for Defect‐Controlled Combination Anticancer Drug Delivery

Author(s): Isabel Abánades Lázaro, Connor J. R. Wells, Ross S. Forgan
Published in: Angewandte Chemie International Edition, Issue 59/13, 2020, Page(s) 5211-5217, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201915848

The surface chemistry of metal–organic frameworks and their applications

Author(s): Ross S. Forgan
Published in: Dalton Transactions, Issue 48/25, 2019, Page(s) 9037-9042, ISSN 1477-9226
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9dt01710k

Modulated self-assembly of metal–organic frameworks

Author(s): Ross S. Forgan
Published in: Chemical Science, Issue 11/18, 2020, Page(s) 4546-4562, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc01356k

Exploring and expanding the Fe-terephthalate metal–organic framework phase space by coordination and oxidation modulation

Author(s): Dominic Bara, Emily G. Meekel, Ignas Pakamorė, Claire Wilson, Sanliang Ling and Ross S. Forgan
Published in: Materials Horizons, Issue 8, 2022, Page(s) 3377-3386, ISSN 2051-6355
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1mh01663f