Mechanisms of protein translocation in ER-associated protein degradation and the related protein import into the apicoplast of Plasmodium falciparum

Project Information

ERAD_SELMA

Grant agreement ID: 677770

DOI 10.3030/677770

Project closed

EC signature date 10 February 2016

Start date 1 March 2016

End date 31 May 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Non-peer reviewed articles (1)

Off and On Again: De- and Reubiquitination during Membrane Protein Degradation

Author(s): Claudia C. Schmidt, Alexander Stein
Published in: Molecular Cell, Issue 79/2, 2020, Page(s) 203-204, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.06.036

Peer reviewed articles (4)

Hrd1 forms the retrotranslocation pore regulated by auto-ubiquitination and binding of misfolded proteins

Author(s): Vedran Vasic, Niels Denkert, Claudia C. Schmidt, Dietmar Riedel, Alexander Stein, Michael Meinecke
Published in: Nature Cell Biology, 2020, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-020-0473-4

Quality Control of Protein Complex Assembly by a Transmembrane Recognition Factor

Author(s): Nivedita Natarajan, Ombretta Foresti, Kim Wendrich, Alexander Stein, Pedro Carvalho
Published in: Molecular Cell, Issue 77/1, 2020, Page(s) 108-119.e9, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.10.003

Doa10 is a membrane protein retrotranslocase in ER-associated protein degradation

Author(s): Claudia C Schmidt, Vedran Vasic, Alexander Stein
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.56945

Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3

Author(s): Stefan Schoebel, Wei Mi, Alexander Stein, Sergey Ovchinnikov, Ryan Pavlovicz, Frank DiMaio, David Baker, Melissa G. Chambers, Huayou Su, Dongsheng Li, Tom A. Rapoport, Maofu Liao
Published in: Nature, Issue 548/7667, 2017, Page(s) 352-355, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature23314