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Cofactor Binding Antibodies – Basic Aspects and Therapeutic Innovations

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Aromatic Guanylhydrazones for the Control of Heme-Induced Antibody Polyreactivity

Author(s): Nina Božinović, Vladimir Ajdačić, Jelena Lazic, Maxime Lecerf, Victoria Daventure, Jasmina Nikodinovic-Runic, Igor M. Opsenica, Jordan D. Dimitrov
Published in: ACS Omega, 4/24, 2019, Page(s) 20450-20458, ISSN 2470-1343
Publisher: American Chemical Society
DOI: 10.1021/acsomega.9b01548

Interaction of clinical-stage antibodies with heme predicts their physiochemical and binding qualities

Author(s): Maxime Lecerf, Alexia Kanyavuz, Sofia Rossini, Jordan D. Dimitrov
Published in: Communications Biology, 4/1, 2021, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-021-01931-7

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

Author(s): Cyril Planchais, Ayrin Kök, Alexia Kanyavuz, Valérie Lorin, Timothée Bruel, Florence Guivel-Benhassine, Tim Rollenske, Julie Prigent, Thierry Hieu, Thierry Prazuck, Laurent Lefrou, Hedda Wardemann, Olivier Schwartz, Jordan D. Dimitrov, Laurent Hocqueloux, Hugo Mouquet
Published in: Cell Reports, 27/2, 2019, Page(s) 572-585.e7, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.03.032

P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner

Author(s): Nicolas S. Merle, Romain Paule, Juliette Leon, Marie Daugan, Tania Robe-Rybkine, Victoria Poillerat, Carine Torset, Véronique Frémeaux-Bacchi, Jordan D. Dimitrov, Lubka T. Roumenina
Published in: Proceedings of the National Academy of Sciences, 116/13, 2019, Page(s) 6280-6285, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1814797116

Anti-inflammatory activity of intravenous immunoglobulin through scavenging of heme

Author(s): Marie Wiatr, Nicolas S. Merle, Idris Boudhabhay, Victoria Poillerat, Sofia Rossini, Maxime Lecerf, Srini V. Kaveri, Sébastian Lacroix-Desmazes, Lubka T. Roumenina, Jordan D. Dimitrov
Published in: Molecular Immunology, 111, 2019, Page(s) 205-208, ISSN 0161-5890
Publisher: Pergamon Press
DOI: 10.1016/j.molimm.2019.04.020

Breaking the law: unconventional strategies for antibody diversification

Author(s): Alexia Kanyavuz, Annaelle Marey-Jarossay, Sébastien Lacroix-Desmazes, Jordan D. Dimitrov
Published in: Nature Reviews Immunology, 2019, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/s41577-019-0126-7

Use of cysteine as a spectroscopic probe for determination of heme-scavenging capacity of serum proteins and whole human serum

Author(s): Rémi Noé, Nina Bozinovic, Maxime Lecerf, Sébastien Lacroix-Desmazes, Jordan D. Dimitrov
Published in: Journal of Pharmaceutical and Biomedical Analysis, 172, 2019, Page(s) 311-319, ISSN 0731-7085
Publisher: Elsevier BV
DOI: 10.1016/j.jpba.2019.05.013