Dissecting the function and regulation of centriolar satellites: key regulators of the centrosome/cilium complex

Project Information

CentSatRegFunc

Grant agreement ID: 679140

DOI

10.3030/679140

Project closed

EC signature date 10 May 2016

Start date 1 June 2016

End date 31 May 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 818,75

EU contribution

€ 1 499 818,75

Coordinated by

KOC UNIVERSITY
Türkiye

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Aurora Kinase A proximity map reveals centriolar satellites as regulators of its ciliary function

Author(s): Melis D. Arslanhan; Navin Rauniyar; John R. Yates; Elif Nur Firat-Karalar
Published in: EMBO Reports, Issue 1, 2021, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.202051902

A Proximity Mapping Journey into the Biology of the Mammalian Centrosome/Cilium Complex

Author(s): Melis Dilara Arslanhan, Dila Gulensoy, Elif Nur Firat-Karalar
Published in: Cells, Issue 9/6, 2020, Page(s) 1390, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells9061390

Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium

Author(s): Özge Z. Aydin, Sevket Onur Taflan, Can Gurkaslar, Elif Nur Firat-Karalar
Published in: PLOS Biology, Issue 18/6, 2020, Page(s) e3000679, ISSN 1545-7885
Publisher: PLOS
DOI: 10.1371/journal.pbio.3000679

CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression

Author(s): H. Kubra Gurkaslar, Efraim Culfa, Melis D. Arslanhan, Mariana Lince-Faria, Elif Nur Firat-Karalar
Published in: Cell Reports, Issue 31/6, 2020, Page(s) 107630, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.107630

The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule nucleation and organization

Author(s): Umut Batman, Jovana Deretic, Elif N Firat-Karalar
Published in: PLOS Biology, 2022, ISSN 1545-7885
Publisher: PLOS
DOI: 10.1371/journal.pbio.3001708

Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors

Author(s): Deniz Conkar, Halil Bayraktar, Elif Nur Firat-Karalar
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-50530-4

The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking

Author(s): Deniz Conkar, Efraim Culfa, Ezgi Odabasi, Navin Rauniyar, John R. Yates, Elif N. Firat-Karalar
Published in: Journal of Cell Science, Issue 130/8, 2017, Page(s) 1450-1462, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.196832

The ciliopathy gene product Cep290 is required for primary cilium formation and microtubule network organization

Author(s): Elif Nur FIRAT-KARALAR
Published in: TURKISH JOURNAL OF BIOLOGY, Issue 42/5, 2018, Page(s) 371-381, ISSN 1300-0152
Publisher: Scientific and Technical research Council of Turkey - TUBITAK/Turkiye Bilimsel ve Teknik Arastirma Kurumu
DOI: 10.3906/biy-1805-25

Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation

Author(s): Ezgi Odabasi, Seref Gul, Ibrahim H Kavakli, Elif N Firat‐Karalar
Published in: EMBO reports, 2019, Page(s) e47723, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.201947723

Unraveling the mysteries of centriolar satellites: time to rewrite the textbooks about the centrosome/cilium complex

Author(s): Ezgi Odabasi, Umut Batman, Elif Nur Firat-Karalar
Published in: Molecular Biology of the Cell, Issue 31/9, 2020, Page(s) 866-872, ISSN 1059-1524
Publisher: American Society for Cell Biology
DOI: 10.1091/mbc.e19-07-0402

CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins

Author(s): Ezgi Odabasi, Deniz Conkar,Jovana Deretic, Umut Batman,Kari-Anne Frikstad, Sebastian Patzke, Elif N Firat-karalar
Published in: Journal of Cell Science, 2023, ISSN 1059-1524
Publisher: American Society for Cell Biology
DOI: 10.1242/jcs.260327