Vaccine profiling and immunodiagnostic discovery by high-throughput antibody repertoire analysis

Project Information

Antibodyomics

Grant agreement ID: 679403

DOI 10.3030/679403

Project closed

EC signature date 25 May 2016

Start date 1 June 2016

End date 31 May 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 492 586,00

EU contribution € 1 492 586,00

Coordinated by

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland

Publications

Peer reviewed articles (5)

Tracing Antibody Repertoire Evolution by Systems Phylogeny

Author(s): Alexander Dimitri Yermanos, Andreas Kevin Dounas, Tanja Stadler, Annette Oxenius, Sai T. Reddy
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2018.02149

Learning the High-Dimensional Immunogenomic Features That Predict Public and Private Antibody Repertoires

Author(s): Victor Greiff, Cédric R. Weber, Johannes Palme, Ulrich Bodenhofer, Enkelejda Miho, Ulrike Menzel, Sai T. Reddy
Published in: The Journal of Immunology, Issue 199/8, 2017, Page(s) 2985-2997, ISSN 0022-1767
Publisher: American Association of Immunologists
DOI: 10.4049/jimmunol.1700594

Integrating high-throughput screening and sequencing for monoclonal antibody discovery and engineering

Author(s): Cristina Parola, Daniel Neumeier, Sai T. Reddy
Published in: Immunology, Issue 153/1, 2018, Page(s) 31-41, ISSN 0019-2805
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/imm.12838

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis

Author(s): Derek M Mason, Cédric R Weber, Cristina Parola, Simon M Meng, Victor Greiff, William J Kelton, Sai T Reddy
Published in: Nucleic Acids Research, Issue 46/14, 2018, Page(s) 7436-7449, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gky550

Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires

Author(s): Enkelejda Miho, Alexander Yermanos, Cédric R. Weber, Christoph T. Berger, Sai T. Reddy, Victor Greiff
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2018.00224