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The Pancreas Regulome: From causality to prediction of non-coding mutations in human pancreatic diseases

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Publications

FOXM1 repression increases mitotic death upon antimitotic chemotherapy through BMF upregulation

Author(s): Sara Vaz, Fábio J. Ferreira, Joana C. Macedo, Gil Leor, Uri Ben-David, José Bessa, Elsa Logarinho
Published in: Cell Death & Disease, 2021, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/s41419-021-03822-5

Glycans as Immune Checkpoints: Removal of Branched N-glycans Enhances Immune Recognition Preventing Cancer Progression

Author(s): Mariana C. Silva, Ângela Fernandes, Maria Oliveira, Carlos Resende, Alexandra Correia, Julio C. de-Freitas-Junior, Aonghus Lavelle, Jéssica Andrade-da-Costa, Magdalena Leander, Helena Xavier-Ferreira, José Bessa, Carina Pereira, Rui M. Henrique, Fátima Carneiro, Mário Dinis-Ribeiro, Ricardo Marcos-Pinto, Margarida Lima, Bernd Lepenies, Harry Sokol, José C. Machado, Manuel Vilanova, Salomé S
Published in: Cancer Immunology Research, 8/11, 2020, Page(s) 1407-1425, ISSN 2326-6066
Publisher: American Association for Cancer Research Inc.
DOI: 10.1158/2326-6066.cir-20-0264

A Conserved Notochord Enhancer Controls Pancreas Development in Vertebrates

Author(s): João Pedro Amorim, Ana Gali-Macedo, Hugo Marcelino, Renata Bordeira-Carriço, Silvia Naranjo, Solangel Rivero-Gil, Joana Teixeira, Mafalda Galhardo, Joana Marques, José Bessa
Published in: Cell Reports, 32/1, 2020, Page(s) 107862, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.107862

foxm1 Modulates Cell Non-Autonomous Response in Zebrafish Skeletal Muscle Homeostasis

Author(s): Fábio J Ferreira; Leonor Carvalho; Leonor Carvalho; Leonor Carvalho; Elsa Logarinho; Elsa Logarinho; José Bessa; José Bessa
Published in: Cells, 1, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10051241

Antisense Transcription across Nucleotide Repeat Expansions in Neurodegenerative and Neuromuscular Diseases: Progress and Mysteries

Author(s): Ana F. Castro, Joana R. Loureiro, José Bessa, Isabel Silveira
Published in: Genes, 11/12, 2020, Page(s) 1418, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes11121418

In Vivo Reporter Assays Uncover Changes in Enhancer Activity Caused by Type 2 Diabetes–Associated Single Nucleotide Polymorphisms

Author(s): Ana Eufrásio, Chiara Perrod, Fábio J. Ferreira, Marta Duque, Mafalda Galhardo, José Bessa
Published in: Diabetes, 69/12, 2020, Page(s) 2794-2805, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/db19-1049

Ptf1a function and transcriptional cis-regulation, a cornerstone in vertebrate pancreas development.

Author(s): Marta Duque; Marta Duque; João Amorim; João Amorim; José Bessa; José Bessa
Published in: FEBS, 1, 2021, ISSN 1742-464X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/febs.16075

CRISPR-Cas9-Mediated Genomic Deletions Protocol in Zebrafish

Author(s): João Pedro Amorim, Renata Bordeira-Carriço, Ana Gali-Macedo, Chiara Perrod, José Bessa
Published in: STAR Protocols, 1/3, 2020, Page(s) 100208, ISSN 2666-1667
Publisher: Cell Press
DOI: 10.1016/j.xpro.2020.100208

Intratumoral VEGF nanotrapper reduces gliobastoma vascularization and tumor cell mass

Author(s): Flávia Sousa; Ana Isabel Costa-Pereira; Andrea Cruz; Fábio J Ferreira; Marcos Gouveia; José Bessa; Bruno Sarmento; Rui D. M. Travasso; I Pinto
Published in: Journal of Controlled Release, 1, 2021, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2021.09.031

Study of human regulatory mutations associated with pancreatic diseases by humanizing the zebrafish genome.

Author(s): Inês Maria Batista da Costa
Published in: University of Oporto, 1, 2019
Publisher: Universidade do Porto

Uncovering transcriptional cisregulatory  elements active in zebrafish adult exocrine pancreas

Author(s): Diogo José Coutinho Ribeiro
Published in: University of Oporto, 1, 2018
Publisher: Universidade do Porto

O potencial regulatório em cis de sequências não codificantes associadas a diabetes tipo 2

Author(s): Eufrásio, Ana Catarina Macedo
Published in: University of Aveiro, 1, 2018
Publisher: Universidade de Aveiro

Cis-regulatory similarities in the zebrafish and human pancreas uncover potential disease-related enhancers

Author(s): R. Bordeira-Carriço ; J. Teixeira ; M. Duque ; M. Galhardo ; D. Ribeiro ; R. Dominguez-Acemel ; P. N. Firbas ; J. J. Tena ; A. Eufrasio; J. Marques ; F. Ferreira ; T. Freitas ; F. Carneiro ; J. L. Goméz-Skarmeta ; J. Bessa
Published in: Biorxvi, 2020
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/2020.04.27.064220

A master cis-regulatory element in the FOXM1/RHNO1/TEAD4 landscape drives cellular senescence

Author(s): Fábio Júnio Ferreira, Joana Teixeira, Mafalda Galhardo, Elsa Logarinho, José Bessa
Published in: Genome Biology, 2022, ISSN 1474-760X
Publisher: BioMed Central