Objective We aim to reduce the burden of tobacco-related lung diseases. Our approach is to integrate inexpensive tobacco cessation strategies of proven efficacy into TB control programmes. This has three advantages: a) Preventing non-communicable diseases as well as reducing TB-related deaths; b) TB patients are more likely to quit tobacco than healthy smokers – ‘teachable moments’; and c) in the absence of specialist infrastructure, an approach to ‘piggyback’ cessation on existing programmes is a desirable policy imperative. We will first assess the effectiveness and cost-effectiveness of tobacco cessation strategies in helping TB patients to quit and improving their TB outcomes - the effectiveness goal; and then explore how best these strategies can be delivered, sustained and scaled-up – the implementation goal. We propose six work packages for Bangladesh, Nepal and Pakistan - high TB and tobacco burden countries.WP1 Development & Feasibility: To optimise the delivery of tobacco cessation strategies within TB programmes (focus group discussions [FGD], interviews, surveys, expert panel workshops)WP2 & 3 Effect and economic evaluation: To assess the effectiveness and cost effectiveness of cytisine with behavioural support vs. behavioural support alone on tobacco cessation and TB outcomes (randomised controlled trial [RCT])WP4 Process evaluation: To study the design and delivery of the tobacco cessation strategies (FGD, observations, exit interviews)WP5 Context evaluation: To study the influence of contextual factors on the RCT outcomes (lit. review, interviews, surveys, analysis)WP6 Scale up & Sustainability: To assess sustainability of the cessation strategies and identify the likely costs, obstacles and opportunities for scaling these up (FGD, interviews, cost and outcomes analysis)Our ambition is that by studying the ‘real world’ influences on the implementation and success of tobacco cessation we will be able to translate our findings into benefits for patients Fields of science medical and health sciencesclinical medicinepneumologymedical and health scienceshealth sciencespublic healthmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugssocial sciencespolitical sciencesgovernment systems Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.3. - Treating and managing disease Topic(s) HCO-06-2015 - Global Alliance for Chronic Diseases. Prevention and treatment of lung diseases Call for proposal H2020-HCO-2014-2015 See other projects for this call Sub call H2020-HCO-2015 Funding Scheme RIA - Research and Innovation action Coordinator UNIVERSITY OF YORK Net EU contribution € 1 085 001,25 Address Heslington YO10 5DD York north yorkshire United Kingdom See on map Region Yorkshire and the Humber North Yorkshire York Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (9) Sort alphabetically Sort by Net EU contribution Expand all Collapse all ARK FOUNDATION Bangladesh Net EU contribution € 477 773,75 Address House no b 130 road no 21 new dohs mohakhali 1206 Dhaka See on map Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 HEALTH RESEARCH AND SOCIAL DEVELOPMENT FORUM Participation ended Nepal Net EU contribution € 0,00 Address Thapathali 11 44601 Kathmandu See on map Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MINISTRY OF NATIONAL HEALTH SERICES, REGULATION AND COORDINATION Participation ended Pakistan Net EU contribution € 113 925,00 Address Lg & rd complex prime ministers national health complex epi building Islamabad See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE INITIATIVE Pakistan Net EU contribution € 430 743,75 Address Orange grove farm mainkorung road 44000 Islamabad See on map Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 HEINRICH-HEINE-UNIVERSITAET DUESSELDORF Germany Net EU contribution € 209 845,00 Address Universitaetsstrasse 1 40225 Dusseldorf See on map Region Nordrhein-Westfalen Düsseldorf Düsseldorf, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE UNIVERSITY OF EDINBURGH United Kingdom Net EU contribution € 60 096,25 Address Old college, south bridge EH8 9YL Edinburgh See on map Region Scotland Eastern Scotland Edinburgh Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY OF LEEDS United Kingdom Net EU contribution € 357 205,00 Address Woodhouse lane LS2 9JT Leeds See on map Region Yorkshire and the Humber West Yorkshire Leeds Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 VSEOBECNA FAKULTNI NEMOCNICE V PRAZE Czechia Net EU contribution € 140 141,25 Address U nemocnice 2 12808 Praha 2 See on map Region Česko Praha Hlavní město Praha Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 HERD INTERNATIONAL PVT LTD Nepal Net EU contribution € 125 097,50 Address Thapathali 11 44601 Kathmandu See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00