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Personalized oncolytic vaccines for cancer immunotherapy

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Publications

A novel in silico framework to improve MHC-I epitopes and break the tolerance to melanoma

Author(s): Cristian Capasso, Aniket Magarkar, Victor Cervera-Carrascon, Manlio Fusciello, Sara Feola, Martin Muller, Mariangela Garofalo, Lukasz Kuryk, Siri Tähtinen, Lucio Pastore, Alex Bunker, Vincenzo Cerullo
Published in: OncoImmunology, Issue 6/9, 2017, Page(s) e1319028, ISSN 2162-402X
DOI: 10.1080/2162402X.2017.1319028

Personalized Cancer Vaccine Platform for Clinically Relevant Oncolytic Enveloped Viruses

Author(s): Erkko Ylösmäki, Cristina Malorzo, Cristian Capasso, Oona Honkasalo, Manlio Fusciello, Beatriz Martins, Leena Ylösmäki, Antti Louna, Sara Feola, Henrik Paavilainen, Karita Peltonen, Veijo Hukkanen, Tapani Viitala, Vincenzo Cerullo
Published in: Molecular Therapy, Issue 26/9, 2018, Page(s) 2315-2325, ISSN 1525-0016
DOI: 10.1016/j.ymthe.2018.06.008

Oncolytic vaccines increase the response to PD-L1 blockade in immunogenic and poorly immunogenic tumors

Author(s): S. Feola, C. Capasso, M. Fusciello, B. Martins, S. Tähtinen, M. Medeot, S. Carpi, F. Frascaro, E. Ylosmäki, K. Peltonen, L. Pastore, V. Cerullo
Published in: OncoImmunology, 2018, Page(s) e1457596, ISSN 2162-402X
DOI: 10.1080/2162402x.2018.1457596

Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the antitumor immunity and efficacy against melanoma

Author(s): Cristian Capasso, Mari Hirvinen, Mariangela Garofalo, Dmitrii Romaniuk, Lukasz Kuryk, Teea Sarvela, Andrea Vitale, Maxim Antopolsky, Aniket Magarkar, Tapani Viitala, Teemu Suutari, Alex Bunker, Marjo Yliperttula, Arto Urtti, Vincenzo Cerullo
Published in: OncoImmunology, Issue 5/4, 2015, Page(s) e1105429, ISSN 2162-402X
DOI: 10.1080/2162402X.2015.1105429

Artificially cloaked viral nanovaccine for cancer immunotherapy

Author(s): Manlio Fusciello, Flavia Fontana, Siri Tähtinen, Cristian Capasso, Sara Feola, Beatriz Martins, Jacopo Chiaro, Karita Peltonen, Leena Ylösmäki, Erkko Ylösmäki, Firas Hamdan, Otto K. Kari, Joseph Ndika, Harri Alenius, Arto Urtti, Jouni T. Hirvonen, Hélder A. Santos, Vincenzo Cerullo
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-13744-8

Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site

Author(s): Alessandra Lopes, Sara Feola, Sophie Ligot, Manlio Fusciello, Gaëlle Vandermeulen, Véronique Préat, Vincenzo Cerullo
Published in: Journal for ImmunoTherapy of Cancer, Issue 7/1, 2019, ISSN 2051-1426
DOI: 10.1186/s40425-019-0644-7

Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor

Author(s): Flavia Fontana, Manlio Fusciello, Christianne Groeneveldt, Cristian Capasso, Jacopo Chiaro, Sara Feola, Zehua Liu, Ermei M. Mäkilä, Jarno J. Salonen, Jouni T. Hirvonen, Vincenzo Cerullo, Hélder A. Santos
Published in: ACS Nano, Issue 13/6, 2019, Page(s) 6477-6490, ISSN 1936-0851
DOI: 10.1021/acsnano.8b09613

Exploiting pre-existing immunity to enhance oncolytic cancer immunotherapy

Author(s): Siri Tähtinen, Sara Feola, Cristian Capasso, Netta Laustio, Christianne Groeneveldt, Erkko O Ylösmäki, Leena Ylösmäki, Beatriz Martins, Manlio Fusciello, Marta Medeot, Maria Tagliamonte, Jacopo Chiaro, Firas Hamdan, Karita Peltonen, Tuuli Ranki, Luigi Buonaguro, Vincenzo Cerullo
Published in: Cancer Research, 2020, Page(s) canres.2062.2019, ISSN 0008-5472
DOI: 10.1158/0008-5472.can-19-2062

Design and application of oncolytic viruses for cancer immunotherapy

Author(s): Erkko Ylösmäki, Vincenzo Cerullo
Published in: Current Opinion in Biotechnology, Issue 65, 2020, Page(s) 25-36, ISSN 0958-1669
DOI: 10.1016/j.copbio.2019.11.016