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Discovery of novel orphan riboswitch ligands


Synthesis of All Possible Canonical (3′–5′-Linked) Cyclic Dinucleotides and Evaluation of Riboswitch Interactions and Immune-Stimulatory Effects

Author(s): Changhao Wang, Malte Sinn, Julia Stifel, Anna C. Heiler, Annette Sommershof, Jörg S. Hartig
Published in: Journal of the American Chemical Society, Issue 139/45, 2017, Page(s) 16154-16160, ISSN 0002-7863
DOI: 10.1021/jacs.7b06141

Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate

Author(s): Sebastian Knorr, Malte Sinn, Dmitry Galetskiy, Rhys M. Williams, Changhao Wang, Nicolai Müller, Olga Mayans, David Schleheck, Jörg S. Hartig
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
DOI: 10.1038/s41467-018-07563-6