Biomechanics and signaling in models of congenital heart valve defects

Project Information

EVALVE

Grant agreement ID: 682938

DOI

10.3030/682938

Project closed

EC signature date 25 November 2016

Start date 1 December 2016

End date 31 May 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis

Author(s): Hélène Vignes, Christina Vagena-Pantoula, Mangal Prakash, Hajime Fukui, Caren Norden, Naoki Mochizuki, Florian Jug, Julien Vermot
Published in: Developmental Cell, Issue 57, 2023, Page(s) 598-609.e5, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2022.02.011

Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta

Author(s): Pedro Campinho, Paola Lamperti, Francesco Boselli, Andrej Vilfan, Julien Vermot
Published in: Cell Reports, Issue 31, 2024, Page(s) 107505, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.03.069

Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling

Author(s): Renee Wei-Yan Chow, Hajime Fukui, Wei Xuan Chan, Kok Soon Justin Tan, Stéphane Roth, Anne-Laure Duchemin, Nadia Messaddeq, Hiroyuki Nakajima, Fei Liu, Nathalie Faggianelli-Conrozier, Andrey S. Klymchenko, Yap Choon Hwai, Naoki Mochizuki, Julien Vermot
Published in: PLOS Biology, Issue 20, 2023, Page(s) e3001505, ISSN 1545-7885
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3001505

The cilium as a force sensor−myth versus reality

Author(s): Rita R. Ferreira, Hajime Fukui, Renee Chow, Andrej Vilfan, Julien Vermot
Published in: Journal of Cell Science, Issue 132/14, 2019, Page(s) jcs213496, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.213496

Chiral Cilia Orientation in the Left-Right Organizer

Author(s): Rita R. Ferreira, Guillaume Pakula, Lhéanna Klaeyle, Hajime Fukui, Andrej Vilfan, Willy Supatto, Julien Vermot
Published in: Cell Reports, Issue 25/8, 2018, Page(s) 2008-2016.e4, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2018.10.069

Three-dimensional microscopy and image analysis methodology for mapping and quantification of nuclear positions in tissues with approximate cylindrical geometry

Author(s): Pedro Campinho, Paola Lamperti, Francesco Boselli, Julien Vermot
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 373/1759, 2018, Page(s) 20170332, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2017.0332

Following Endocardial Tissue Movements via Cell Photoconversion in the Zebrafish Embryo

Author(s): Renee Wei-Yan Chow, Paola Lamperti, Emily Steed, Francesco Boselli, Julien Vermot
Published in: Journal of Visualized Experiments, Issue 132, 2018, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/57290

Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis

Author(s): Lauren M. Goddard, Anne-Laure Duchemin, Harini Ramalingan, Bingruo Wu, Mei Chen, Sharika Bamezai, Jisheng Yang, Li Li, Michael P. Morley, Tao Wang, Marielle Scherrer-Crosbie, David B. Frank, Kurt A. Engleka, Stephen C. Jameson, Edward E. Morrisey, Thomas J. Carroll, Bin Zhou, Julien Vermot, Mark L. Kahn
Published in: Developmental Cell, Issue 43/3, 2017, Page(s) 274-289.e5, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2017.09.023

The rise of photoresponsive protein technologies applications in vivo: a spotlight on zebrafish developmental and cell biology

Author(s): Renee Wei-Yan Chow, Julien Vermot
Published in: F1000Research, Issue 6, 2017, Page(s) 459, ISSN 2046-1402
Publisher: F1000 Research Ltd.
DOI: 10.12688/f1000research.10617.1

Bioelectric signaling and the control of cardiac cell identity in response to mechanical forces

Author(s): Hajime Fukui, Renee Wei-Yan Chow, Jing Xie, Yoke Yin Foo, Choon Hwai Yap, Nicolas Minc, Naoki Mochizuki, Julien Vermot
Published in: Science, Issue 374, 2024, Page(s) 351-354, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abc6229

Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis

Author(s): Marina Peralta, Laia Ortiz Lopez, Katerina Jerabkova, Tommaso Lucchesi, Benjamin Vitre, Dong Han, Laurent Guillemot, Chaitanya Dingare, Izabela Sumara, Nadia Mercader, Virginie Lecaudey, Benedicte Delaval, Sigolène M. Meilhac, Julien Vermot
Published in: Cell Reports, Issue 32, 2022, Page(s) 107932, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.107932