MesopOrous matrices for localiZed pH-triggered releAse of theRapeuTic ions and drugs

Project Information

MOZART

Grant agreement ID: 685872

DOI 10.3030/685872

Project closed

EC signature date 21 September 2015

Start date 1 November 2015

End date 31 October 2019

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies

Total cost € 4 651 228,75

EU contribution € 4 651 228,75

Coordinated by

POLITECNICO DI TORINO
Italy

Publications

Peer reviewed articles (17)

In Vivo Validation of Spray-Dried Mesoporous Bioactive Glass Microspheres Acting as Prolonged Local Release Systems for BMP-2 to Support Bone Regeneration

Author(s): Julia C. Berkmann, Aaron X. Herrera Martin, Carlotta Pontremoli, Kai Zheng, Christian H. Bucher, Agnes Ellinghaus, Aldo R. Boccaccini, Sonia Fiorilli, Chiara Vitale Brovarone, Georg N. Duda, Katharina Schmidt-Bleek
Published in: Pharmaceutics, Issue 12/9, 2020, Page(s) 823, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12090823

Multifunctional Copper-Containing Mesoporous Glass Nanoparticles as Antibacterial and Proangiogenic Agents for Chronic Wounds

Author(s): Thomas E. Paterson, Alessandra Bari, Anthony J. Bullock, Robert Turner, Giorgia Montalbano, Sonia Fiorilli, Chiara Vitale-Brovarone, Sheila MacNeil, Joanna Shepherd
Published in: Frontiers in Bioengineering and Biotechnology, Issue 8, 2020, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2020.00246

Hybrid injectable platforms for the in situ delivery of therapeutic ions from mesoporous glasses

Author(s): C. Pontremoli, M. Boffito, S. Fiorilli, R. Laurano, A. Torchio, A. Bari, C. Tonda-Turo, G. Ciardelli, C. Vitale-Brovarone
Published in: Chemical Engineering Journal, Issue 340, 2018, Page(s) 103-113, ISSN 1385-8947
Publisher: Elsevier BV
DOI: 10.1016/j.cej.2018.01.073

The haematoma and its role in bone healing

Author(s): H. Schell, G. N. Duda, A. Peters, S. Tsitsilonis, K. A. Johnson, K. Schmidt-Bleek
Published in: Journal of Experimental Orthopaedics, Issue 4/1, 2017, ISSN 2197-1153
Publisher: Springer Nature
DOI: 10.1186/s40634-017-0079-3

Comparison of the effects of 45S5 and 1393 bioactive glass microparticles on hMSC behavior

Author(s): Taimoor H. Qazi, Shahzad Hafeez, Jochen Schmidt, Georg N. Duda, Aldo R. Boccaccini, Evi Lippens
Published in: Journal of Biomedical Materials Research Part A, Issue 105/10, 2017, Page(s) 2772-2782, ISSN 1549-3296
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jbm.a.36131

The Incorporation of Strontium to Improve Bone-Regeneration Ability of Mesoporous Bioactive Glasses

Author(s): Sonia Fiorilli, Giulia Molino, Carlotta Pontremoli, Giorgio Iviglia, Elisa Torre, Clara Cassinelli, Marco Morra, Chiara Vitale-Brovarone
Published in: Materials, Issue 11/5, 2018, Page(s) 678, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma11050678

Self-immolative chemistry in nanomedicine.

Author(s): Gisbert-Garzarán M, Manzano M, Vallet-Regí M.
Published in: Chemical Engineering Journal, 2017, ISSN 1385-8947
Publisher: Elsevier BV
DOI: 10.1016/j.cej.2017.12.098

Ag modified mesoporous bioactive glass nanoparticles for enhanced antibacterial activity in 3D infected skin model

Author(s): Kai Zheng, Preethi Balasubramanian, Thomas E. Paterson, Rene Stein, Sheila MacNeil, Sonia Fiorilli, Chiara Vitale-Brovarone, Joanna Shepherd, Aldo R. Boccaccini
Published in: Material Sciences & Engineering C, 2019, ISSN 0928-4931
Publisher: Elsevier BV
DOI: 10.1016/j.msec.2019.109764

Injectable thermosensitive polyurethane hydrogels for sustained co-delivery of functional ions and drugs

Author(s): M. Boffito, C. Pontremoli, S. Fiorilli, R. Laurano, G. Ciardelli, C. Vitale-Brovarone
Published in: Pharmaceutics, 2019, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)

Bacteria induced pH changes in tissue-engineered human skin detected noninvasively using Raman confocal spectroscop

Author(s): Anthony J. Bullock, Marcela Garcia, Joanna Shepherd, Ihtesham Rehman & MacNeil Sheila
Published in: Applied Spectroscopy Reviews, 2019, ISSN 0570-4928
Publisher: Marcel Dekker Inc.

<p>Silver Decorated Mesoporous Carbons for the Treatment of Acute and Chronic Wounds, in a Tissue Regeneration Context</p>

Author(s): Elisa Torre, Dimitra Giasafaki, Theodore Steriotis, Clara Cassinelli, Marco Morra, Sonia Fiorilli, Chiara Vitale-Brovarone, Georgia Charalambopoulou, Giorgio Iviglia
Published in: International Journal of Nanomedicine, Issue Volume 14, 2019, Page(s) 10147-10164, ISSN 1178-2013
Publisher: DovePress
DOI: 10.2147/ijn.s234393

pH-Responsive Mesoporous Silica and Carbon Nanoparticles for Drug Delivery

Author(s): Miguel Gisbert-Garzarán, Miguel Manzano, María Vallet-Regí
Published in: Bioengineering, Issue 4/1, 2017, Page(s) 3, ISSN 2306-5354
Publisher: MDPI (Multidisciplinary Digital Publishing Institute)
DOI: 10.3390/bioengineering4010003

Self-immolative polymers as novel pH-responsive gate keepers for drug delivery

Author(s): M. Gisbert-Garzaran, D. Lozano, M. Vallet-Regí, M. Manzano
Published in: RSC Adv., Issue 7/1, 2017, Page(s) 132-136, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/C6RA26771H

Copper-containing mesoporous bioactive glass nanoparticles as multifunctional agent for bone regeneration

Author(s): Alessandra Bari, Nora Bloise, Sonia Fiorilli, Giorgia Novajra, Maria Vallet-Regí, Giovanna Bruni, Almudena Torres-Pardo, José M. González-Calbet, Livia Visai, Chiara Vitale-Brovarone
Published in: Acta Biomaterialia, 2017, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2017.04.012

Composite Biomaterials Based on Sol-Gel Mesoporous Silicate Glasses: A Review

Author(s): Francesco Baino, Sonia Fiorilli, Chiara Vitale-Brovarone
Published in: Bioengineering, Issue 4/1, 2017, Page(s) 15, ISSN 2306-5354
Publisher: MDPI
DOI: 10.3390/bioengineering4010015

Tuning mesoporous silica dissolution in physiological environments: a review

Author(s): Juan L. Paris, Montserrat Colilla, Isabel Izquierdo-Barba, Miguel Manzano, María Vallet-Regí
Published in: Journal of Materials Science, 2017, ISSN 0022-2461
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10853-017-0787-1

Antioxidant mesoporous Ce-doped bioactive glass nanoparticles with anti-inflammatory and pro-osteogenic activities

Author(s): Kai Zheng, Elisa Torre, Alessandra Bari, Nicola Taccardi, Clara Cassinelli, Marco Morra, Sonia Fiorilli, Chiara Vitale-Brovarone, Giorgio Iviglia, Aldo R. Boccaccini
Published in: Materials Today Bio, Issue 5, 2020, Page(s) 100041, ISSN 2590-0064
Publisher: Elsevier
DOI: 10.1016/j.mtbio.2020.100041