Deliverables
UCPH will provide advice to EMU in analyzing their potential market and developing a go-to-market strategy. This will include determining what if any intellectual property rights can be asserted on the procedures or products that are developed. It will also examine production issues such as scalability and distribution. Financial issues such as pricing strategies, marketing and investments required will also be considered.
Infrastructure Development StrategyEMU with UCPH assistance will create a strategy for increasing its research excellence through changes in facilities and equipment. The plan will: • Assess the feasibility of EMU reaching a standard of excellence while continuing to use partner facilities in Estonia or abroad • Make a cost-benefit analysis to compare the anticipated scientific benefits to the purchase, operating and maintenance costs of new or upgraded infrastructure in the short, intermediate and long term. • Identify potential sources of funding that could support the upgrade of EMU facilities. This includes state, EU and international programmes as well as alternative financing scheme. The plan will be completed in Month 25. • Determine how EMU should proceed to ensure that it can reach research excellence, be capable of scaling up of embryo production and improve animal welfare.
One Technology Transfer Plan for Bovine Embryo ProductionUCPH will help EMU develop its strategy, answering questions of legal arrangements, intellectual property, risk assessments, and financing needs. All of these questions will be addressed in a technology transfer plan.
Bovine IVF Embryo Production PlanExperts from USFD will work with EMU researchers to create a plan that will lay out how EMU can scale up production of bovine IVF embryos for potential commercialization.
Data Management PlanEMU will prepare detailed protocols for storing and managing animal reproductive data. The plan will lay out how the data should be managed over the long term so that it can be used in comparisons with other samples to identify changes over time.
UCPH will work with EMU to map out the potential methods of commercializing its bovine embryo development techniques. The analysis will include the following: • Providing technology transfer consultation - teaching animal breeders how to produce high quality embryos on their own using the techniques developed at EMU. Perhaps via licensing agreements. • Partnerships for embryo production – working with one or more partners to produce and sell high quality embryos to animal breeders in the Baltics, Ukraine, Belarus, Russia and/or other markets
Submit at least 4 journal articles on animal reproduction or embryo analysis (at least 2 with USFD or UCPH)EMU will submit articles to high impact or niche journals.
One Scenario Analysis on potential methods of working with the pharmaceutical sectorEMU, with the help of partners will analyse 3 potential scenarios in regards to working with the pharmaceutical industry. For each method, UTARTU will assess feasibility in terms of infrastructure requirements, potential yields, timeframes for development and initial demand. • Transgenic farm animals as bioreactors to synthesize biopharmaceutical products such as peptides and hormones: This is the scenario that EMU has made the most progress towards, • Transgenic animals as test subjects for drug development where phenotypic and epigenetic information can be monitored. • Inheritable genetic modification to produce animals as bioreactors or test subjects
Publications
Author(s):
K. Leisson, K. Alev, P. Kaasik, T. Kaart, Ü. Jaakma, T. Seene
Published in:
Livestock Science, Issue 18711413, 2013, Page(s) 263-270, ISSN 1871-1413
Publisher:
Elsevier BV
DOI:
10.1016/j.livsci.2013.05.028
Author(s):
M. N�mm, E. Mark, K. Kilk, S. K�ks, �. Jaakma
Published in:
Reproduction, Fertility and Development, Issue 10313613, 2015, Page(s) 135, ISSN 1031-3613
Publisher:
Commonwealth Scientific and Industrial Research Organization Publishing
DOI:
10.1071/RDv27n1Ab85
Author(s):
Sulev Kõks, Rutt Lilleoja, Ene Reimann, Andres Salumets, Paula Reemann, Ülle Jaakma
Published in:
Mammalian Genome, Issue 09388990, 2013, Page(s) 309-321, ISSN 0938-8990
Publisher:
Springer Verlag
DOI:
10.1007/s00335-013-9464-0
Author(s):
G. Sveberg, A.O. Refsdal, H.W. Erhard, E. Kommisrud, M. Aldrin, I.F. Tvete, F. Buckley, A. Waldmann, E. Ropstad
Published in:
Journal of Dairy Science, Issue 00220302, 2013, Page(s) 4375-4386, ISSN 0022-0302
Publisher:
American Dairy Science Association
DOI:
10.3168/jds.2012-6407
Author(s):
P. Pärn, M. Plaas, M. Nõmm, Ü. Jaakma, S. Kõks
Published in:
Reproduction, Fertility and Development, Issue 10313613, 2013, Page(s) 172, ISSN 1031-3613
Publisher:
Commonwealth Scientific and Industrial Research Organization Publishing
DOI:
10.1071/RDv25n1Ab49
Author(s):
K. Elkjær, M.-L. Ancker, H. Gustafsson, N.C. Friggens, A. Waldmann, L. Mølbak, H. Callesen
Published in:
Animal Reproduction Science, Issue 03784320, 2013, Page(s) 39-48, ISSN 0378-4320
Publisher:
Elsevier BV
DOI:
10.1016/j.anireprosci.2013.01.016
Author(s):
Martin, A.D.; Afseth, N.K.; Kohler, A.; Randby, Å.; Eknæs, M., Waldmann, A.; Dørum, G.; Måge, I; Reksen, O.
Published in:
Journal of Dairy Science, Issue 00220302, 2015, ISSN 0022-0302
Publisher:
American Dairy Science Association
DOI:
10.3168/jds.2015-9343
Author(s):
G. Sveberg, G.W. Rogers, J. Cooper, A.O. Refsdal, H.W. Erhard, E. Kommisrud, F. Buckley, A. Waldmann, E. Ropstad
Published in:
Journal of Dairy Science, Issue 00220302, 2015, Page(s) 2450-2461, ISSN 0022-0302
Publisher:
American Dairy Science Association
DOI:
10.3168/jds.2014-8905
Author(s):
Sergo Kasvandik, Gerly Sillaste, Agne Velthut-Meikas, Aavo-Valdur Mikelsaar, Triin Hallap, Peeter Padrik, Tanel Tenson, Ülle Jaakma, Sulev Kõks, Andres Salumets
Published in:
PROTEOMICS, Issue 16159853, 2015, Page(s) 1906-1920, ISSN 1615-9853
Publisher:
John Wiley & Sons Ltd.
DOI:
10.1002/pmic.201400297
Author(s):
U. Tuppits, T. Orro, S. Einarsson, K. Kask, A. Kavak
Published in:
Animal Reproduction Science, Issue 03784320, 2014, Page(s) 182-186, ISSN 0378-4320
Publisher:
Elsevier BV
DOI:
10.1016/j.anireprosci.2014.02.007
Author(s):
Jeremejeva, J.; Orro, T.; Kask, K.
Published in:
Veterinarija ir Zootechnika, 2015, ISSN 1392-2130
Publisher:
Lietuvos Veterinarijos Akademija
Author(s):
E. Nahkur, E. Ernits, V. Andrianov, M. Jalakas, E. Järv
Published in:
Anatomia, Histologia, Embryologia, Issue 03402096, 2014, Page(s) 273-281, ISSN 0340-2096
Publisher:
Blackwell Publishing Inc.
DOI:
10.1111/ahe.12072
Author(s):
Suitso, I.; Jõgi, E.; Orro, T.; Kavak, A.; Kalmus, K.; Viltrop, A.; Nurk, A.
Published in:
Veterinarija ir Zootechnica, 2014, ISSN 1392-2130
Publisher:
Lietuvos Veterinarijos Akademija
Author(s):
Hussar, Piret; Järveots, Tõnu; Jalakas, Mihkel
Published in:
Papers on Anthropology, Issue 14060140, 2015, ISSN 1406-0140
Publisher:
University of Tartu Press
DOI:
10.12697/issn1406-0140
Author(s):
Waldmann, A.; Valdmann, M.; Kurykin, J.; Mällo, G.-K.; Kaart, T.; Larsen, T.
Published in:
15th International Conference on Production Diseases on Farm Animals. Book of Abstracts, 2013
Publisher:
Swedish University of Agricultural Sciences
Author(s):
Arney, David; Jaakson, Hanno; Henno, Merike; Valdmann, Andres; Ling, Katri
Published in:
Proceedings of the First DairyCare Conference 2014, 2014, ISBN 9780993017605
Publisher:
DairyCare COST Action FA1308
Author(s):
Waldmann, A.; Valdmann, M.; Kurykin, J.; Mällo, G.-K.; Kaart, T.; Larsen, T.
Published in:
UTERINE HEALTH. Proceedings from a European seminar in Uppsala, Sweden, November 7, 2013., 2014, ISBN 978-91-576-9193-4
Publisher:
SLU Service/Repro
Author(s):
Waldmann, A.; Raud, A.
Published in:
Reproduction in Domestic Animals, 2015
Publisher:
Wiley-Blackwell
Author(s):
Waldmann, A.; Valdmann, M.; Kurykin, J.; Kaart, T.; Mällo, G.-K. In: JL Juengel, A Miyamoto, C Price, LP Reynolds, MF Smith, R Webb.
Published in:
Proceedings of the Ninth International Symposium on Reproduction in Domestic Ruminants, 2014, ISBN 9781899043637
Publisher:
Context Productions Ltd.
Author(s):
Kiiver, H.; Kommisrud, E.; Soidra, K.; Waldmann, A.
Published in:
Reproduction in Domestic Animals, 2015
Publisher:
Wiley-Blackwell
Author(s):
Kavak, Ants; Kütt, Pille; Kaart, Tanel
Published in:
Reproduction in Domestic Animals, 2015
Publisher:
Blackwell Verlag Gmbh
Author(s):
Kavak, Ants; Kütt, Pille; Kaart, Tanel
Published in:
Reproduction in Domestic Animals, 2014
Publisher:
Blackwell Verlag Gmbh
Author(s):
Nahkur, E.; Ernits, E.; Andrianov, V.; Jalakas, M.; Järv, E.
Published in:
Anatomia, Histologia, Embryologia, 2014
Publisher:
Blackwell Verlag Gmbh
Author(s):
Tuppits, Ulrika; Orro, Toomas; Einarsson, Stig; Salumets, Andres; Truu, Jaak; Kavak, Ants
Published in:
Reproduction in Domestic Animals, 2014
Publisher:
Blackwell Verlag Gmbh
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